Frakturrisikoevaluation mithilfe verschiedener nationaler und internationaler Risikoscores bei Männern

Witzel, Judith Charlotte

dc.contributor.advisor	Siggelkow, Heide Prof. Dr.
dc.contributor.author	Witzel, Judith Charlotte
dc.date.accessioned	2020-08-03T07:02:39Z
dc.date.available	2020-09-03T22:50:03Z
dc.date.issued	2020-08-03
dc.identifier.uri	http://hdl.handle.net/21.11130/00-1735-0000-0005-1443-9
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-8129
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-8129
dc.language.iso	deu	de
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc	610	de
dc.title	Frakturrisikoevaluation mithilfe verschiedener nationaler und internationaler Risikoscores bei Männern	de
dc.type	doctoralThesis	de
dc.title.translated	National and international osteoporosis fracture evaluation in men	de
dc.contributor.referee	Weiser, Lukas PD Dr.
dc.date.examination	2020-08-26
dc.description.abstracteng	Different national and international scores are in use to evaluate the osteoporotic fracture probability in men. The DVO-Score is mainly established in Germany and calculates the 10-year-fracture probability, whereas the FRAX-Score is adopted worldwide. However, also in Germany the FRAX-Score is partly in use. FRAX calculates a 10-year-fracture-probability for four subscores (major osteoporotic fracture (MOF) and hip fracture (HF) with or without including osteodensitometry (OD)). We used established fracture probability scores (DVO, FRAX-Score with OD) and not established ("FRAX+", C. Glüer) scores to calculate the 10-year-fracture probability. Patient files were analyzed for DVO-based 10-year fracture probabilities and for data for the calculation of FRAX-Score for MOF and HF including OD. We used a therapeutic threshold of >30% for the DVO-Score and published thresholds ≥ 20% for MOF and ≥ 3% for HF for the FRAX-Score with OD. 10-year fracture probability was calculated for all 130 patients with OD. Conclusively the scores identify different male patients with indication for therapy, in our male patients the difference predominantly dependent on the RF age and BMD. We suggest careful consideration of the appropriate score in the daily care, especially in young male patients.	de
dc.contributor.coReferee	Schön, Margarete Prof. Dr.
dc.subject.eng	osteoporosis	de
dc.subject.eng	DXA	de
dc.subject.eng	FRAX	de
dc.subject.eng	DVO	de
dc.subject.eng	bone minderal densitiy	de
dc.subject.eng	secondary osteoporosis	de
dc.identifier.urn	urn:nbn:de:gbv:7-21.11130/00-1735-0000-0005-1443-9-2
dc.affiliation.institute	Medizinische Fakultät	de
dc.subject.gokfull	Medizin	de
dc.subject.gokfull	Orthopädie (PPN619876204)	de
dc.description.embargoed	2020-09-03
dc.identifier.ppn	1726109852

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Human- und Zahnmedizin [2877]

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