| dc.contributor.advisor | Paulus, Walter Prof. Dr. | |
| dc.contributor.author | Zmeykina, Elina | |
| dc.date.accessioned | 2021-11-18T09:13:39Z | |
| dc.date.available | 2021-11-25T00:50:04Z | |
| dc.date.issued | 2021-11-18 | |
| dc.identifier.uri | http://hdl.handle.net/21.11130/00-1735-0000-0008-5991-0 | |
| dc.identifier.uri | http://dx.doi.org/10.53846/goediss-8544 | |
| dc.identifier.uri | http://dx.doi.org/10.53846/goediss-8544 | |
| dc.language.iso | eng | de |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject.ddc | 570 | de |
| dc.title | Manipulating neuronal communication by using low-intensity repetitive transcranial magnetic stimulation combined with electroencephalogram | de |
| dc.type | cumulativeThesis | de |
| dc.contributor.referee | Paulus, Walter Prof. Dr. | |
| dc.date.examination | 2021-03-23 | |
| dc.description.abstracteng | Repetitive transcranial magnetic stimulation (rTMS) modulates ongoing brain rhythms by activating neuronal structures and evolving different neuronal mechanisms. In the current work, the role of stimulation strength and frequency for brain rhythms was studied. We hypothesized that a weak oscillating electric field induced by low-intensity rTMS could induce entrainment effects in the brain. To test the hypothesis, we conducted three separate experiments, in which we stimulated healthy human participants with rTMS. We individualized stimulation parameters using computational modeling of induced electric fields in the targets and individual frequency estimated by electroencephalography (EEG). We demonstrated the immediately induced entrainment of occipito-parietal and sensorimotor mu-alpha rhythm by low-intensity rTMS that resulted in phase and amplitude changes measured by EEG. Additionally, we found long-lasting corticospinal excitability changes in the motor cortex measured by motor evoked potentials from the corresponding musle. | de |
| dc.contributor.coReferee | Wörgötter, Florentin Prof. Dr. | |
| dc.subject.eng | transcranial magnetic stimulation | de |
| dc.subject.eng | brain oscillation | de |
| dc.subject.eng | alpha rhythm | de |
| dc.subject.eng | weak electric field | de |
| dc.subject.eng | computational model | de |
| dc.subject.eng | electroencephalography | de |
| dc.identifier.urn | urn:nbn:de:gbv:7-21.11130/00-1735-0000-0008-5991-0-1 | |
| dc.affiliation.institute | Göttinger Graduiertenschule für Neurowissenschaften, Biophysik und molekulare Biowissenschaften (GGNB) | de |
| dc.subject.gokfull | Biologie (PPN619462639) | de |
| dc.description.embargoed | 2021-11-25 | |
| dc.identifier.ppn | 1777984572 | |