Comparative studies on regulation of SNARE complex formation by the SM protein Sly1p
Vergleichende Studien zur Regulation der SNARE Komplex Bildung durch das SM protein Sly1p
von Fatma Esra Demircioglu
Datum der mündl. Prüfung:2011-11-01
Erschienen:2012-06-11
Betreuer:Prof. Dr. Dirk Fasshauer
Gutachter:Prof. Dr. Dirk Fasshauer
Gutachter:Prof. Dr. Markus Wahl
Gutachter:Prof. Dr. Stefan Eimer
Dateien
Name:demircioglu.pdf
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Format:PDF
Zusammenfassung
Englisch
Sec1/ Munc18 (SM) proteins are indispensible regulators of intracellular membrane fusion. In general, the high-affinity binding partners of SM proteins are Qa-SNAREs (syntaxins). Despite the high structural homology among SM proteins, different modes are proposed for their association with syntaxins. Neuronal Munc18a binds to a ‟closed conformation
Keywords: Membrane fusion; Sly1p; SNARE; syntaxin; Sed5p; ER; Golgi
Schlagwörter: Membranfusion; Sly1p; SNARE; Syntaxin; Sed5p; ER; Golgi