Browsing Molekulare Medizin by Advisor "Hessmann, Elisabeth Prof. Dr."
Now showing items 1-2 of 2
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TP53-status dependent oncogenic EZH2 Activity in Pancreatic Cancer
(2022-07-14)Pancreatic Ductal Adenocarcinoma (PDAC) remains a dismal malignancy with a 5-year sur-vival rate of less than 10%. Predominately, chemoresistance mediated by the dynamic cel-lular plasticity induced through epigenetic ... -
Interplay of ARID1A and EGFR signaling in controlling acinar cell reprogramming in the pancreas
(2021-03-18)Based on a high degree of cellular plasticity and triggered by external (e.g. inflammation) or internal (e.g. oncogenic pressure) signals, pancreatic acinar cells can undergo reprogramming processes resulting in acinar-to-ductal ...