Browsing Molekulare Medizin by Referee "Heßmann, Elisabeth PD Dr."
Now showing items 1-3 of 3
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Spatial Architecture and Functional Characterization of Super Enhancer Associated Transcriptional Circuits in Aggressive Lymphomas
(2023-10-19)Aggressive lymphomas are clinically and biologically heterogenous entities, reflecting a diverse cell of-origins with multiple means of malignant transformation. With chemoimmunotherapy, a majority of patients suffering ... -
EZH2-GATA6 axis in Pancreatic ductal adenocarcinoma
(2020-09-25)Pancreatic ductal adenocarcinoma (PDAC) is a highly heterogeneous disease which is significantly driven by epigenetic alterations, e.g. installed by overexpression of Enhancer of Zeste homologue 2 (EZH2). EZH2 constitutes ... -
Nuclear NFATc1/Smad3 complexes in Smad4-deficient pancreatic cancer
(2019-12-17)Until today, pancreatic ductal adenocarcinoma (PDAC) is characterized by its extremely high mortality rate and the lack of effective treatment strategies despite reinforced focus on the elucidation of underlying molecular ...