dc.contributor.advisor | Miosge, Nicolai Prof. Dr. | |
dc.contributor.author | Marks, Phillip | |
dc.date.accessioned | 2016-03-22T12:11:24Z | |
dc.date.available | 2016-03-31T22:50:07Z | |
dc.date.issued | 2016-03-22 | |
dc.identifier.uri | http://hdl.handle.net/11858/00-1735-0000-0028-8704-C | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-5578 | |
dc.language.iso | deu | de |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject.ddc | 610 | de |
dc.title | Parakrine Beeinflussung der Genexpression in vitro von chondrogenen Zellen in der Osteoarthrose | de |
dc.type | doctoralThesis | de |
dc.title.translated | Paracrine modulation of the gene-expression in vitro of chondrogenic cells in osteoarthritis | de |
dc.contributor.referee | Behr, Rüdiger Prof. Dr. | |
dc.date.examination | 2016-03-23 | |
dc.description.abstracteng | Analysis of the gene-Expression profiles of mesenchymal stem cells (MSC), chondrogenic progenitor cells (CPC) and Chondrocytes in 3D-Coculture-Systems and in conditions with osteoarthrotic conditioned culture media. The results show CPC in similar potential of paracrine Mediation as MSC. Further we could prove indifferent trophic mediation of osteoarthritic cartilage independently from the grade of degradation. | de |
dc.contributor.coReferee | Schön, Margarete Prof. Dr. | |
dc.subject.ger | Osteoarthrose | de |
dc.subject.ger | Mesenchymale Stammzellen | de |
dc.subject.ger | Chondrogene Progenitorzellen | de |
dc.subject.ger | Genexpression | de |
dc.subject.ger | parakrin | de |
dc.subject.ger | Gelenkknorpel | de |
dc.subject.eng | mesenchymal stem cells | de |
dc.subject.eng | chondrogenic progenitor cells | de |
dc.subject.eng | cartilage | de |
dc.subject.eng | paracrine | de |
dc.subject.eng | gene expression | de |
dc.identifier.urn | urn:nbn:de:gbv:7-11858/00-1735-0000-0028-8704-C-4 | |
dc.affiliation.institute | Medizinische Fakultät | de |
dc.subject.gokfull | Medizin (PPN619874732) | de |
dc.description.embargoed | 2016-03-31 | |
dc.identifier.ppn | 853775915 | |