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dc.contributor.advisor Wedekind, Dirk PD Dr.
dc.contributor.author Giller, Teresa
dc.date.accessioned 2016-11-10T10:08:23Z
dc.date.available 2016-11-22T23:50:05Z
dc.date.issued 2016-11-10
dc.identifier.uri http://hdl.handle.net/11858/00-1735-0000-002B-7C9E-1
dc.language.iso deu de
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc 610 de
dc.title Psychopharmakotherapie in der stationären Medikamentenentzugsbehandlung - eine retrospektive Untersuchung der psychiatrischen Behandlungspraxis de
dc.type doctoralThesis de
dc.title.translated Psychopharmacotherapy in the withdrawal treatment of inpatients with substance use disorder de
dc.contributor.referee Alt-Epping, Bernd Prof. Dr.
dc.date.examination 2016-11-15
dc.description.abstracteng Despite the high clinical relevance, established guidelines for benzodiazepine-, and in particular opioid addiction are still scarce. In a retrospective design, treatment variables of inpatients with benzodiazepine- and opioid-addiction or abuse were recorded according to patients´ charts. Groups comprising patients with benzodiazepine/non-benzodiazepine abuse/addiction, opioid- and non-opioid analgetic abuse/addiction were established. 92% of all patients actually received additional pharmacologic treatment. Before all, antidepressants were prescribed (76%), but also mood-stabilizers/anticonvulsants (27%), and neuroleptic drugs (11%). Antidepressant treatment was tricyclic/tetracyclic treatment almost exclusively. Anticonvulsants, in most cases carbamazepine, was mostly prescribed for patients with combined drug use or high-dose benzodiazepine addiction, who were significantly more often treated with anticonvulsants compared to low-dose addicted subjects. Despite a negative recommendation according to AWMF-guidelines for medication addiction, low potential neuroleptic drugs were used frequently in all patient groups. 80% of included subjects had at least one comorbid psychiatric condition, before all depressive disorder, anxiety disorders, PTSD, and other adjustment disorders. 67% of patients described traumatic life-events. These were significantly more often found in high-dose compared to low dose benzodiazepine addicted patients. de
dc.contributor.coReferee Meyer, Thomas Prof. Dr.
dc.subject.ger Benzodiazepin de
dc.subject.ger Opioidanalgetika de
dc.subject.ger Nichtopioidanalgetika de
dc.subject.ger Psychopharmakotherapie de
dc.subject.ger stationäre de
dc.subject.ger Medikamentenentzugsbehandlung de
dc.subject.ger Entzug de
dc.subject.ger Entzugsbehandlung de
dc.subject.eng substance de
dc.subject.eng opioid de
dc.subject.eng addiction de
dc.subject.eng benzodiazepine de
dc.subject.eng non-benzodiazepine de
dc.subject.eng abuse de
dc.subject.eng non-opioid de
dc.subject.eng withdrawal de
dc.subject.eng psychopharmacotherapy de
dc.identifier.urn urn:nbn:de:gbv:7-11858/00-1735-0000-002B-7C9E-1-5
dc.affiliation.institute Medizinische Fakultät de
dc.subject.gokfull Medizin (PPN619874732) de
dc.description.embargoed 2016-11-22
dc.identifier.ppn 872311821

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