dc.contributor.advisor | Wedekind, Dirk PD Dr. | |
dc.contributor.author | Giller, Teresa | |
dc.date.accessioned | 2016-11-10T10:08:23Z | |
dc.date.available | 2016-11-22T23:50:05Z | |
dc.date.issued | 2016-11-10 | |
dc.identifier.uri | http://hdl.handle.net/11858/00-1735-0000-002B-7C9E-1 | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-5936 | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-5936 | |
dc.language.iso | deu | de |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject.ddc | 610 | de |
dc.title | Psychopharmakotherapie in der stationären Medikamentenentzugsbehandlung - eine retrospektive Untersuchung der psychiatrischen Behandlungspraxis | de |
dc.type | doctoralThesis | de |
dc.title.translated | Psychopharmacotherapy in the withdrawal treatment of inpatients with substance use disorder | de |
dc.contributor.referee | Alt-Epping, Bernd Prof. Dr. | |
dc.date.examination | 2016-11-15 | |
dc.description.abstracteng | Despite the high clinical relevance, established guidelines for benzodiazepine-, and in particular opioid addiction are still scarce.
In a retrospective design, treatment variables of inpatients with benzodiazepine- and opioid-addiction or abuse were recorded according to patients´ charts. Groups comprising patients with benzodiazepine/non-benzodiazepine abuse/addiction, opioid- and non-opioid analgetic abuse/addiction were established.
92% of all patients actually received additional pharmacologic treatment. Before all, antidepressants were prescribed (76%), but also mood-stabilizers/anticonvulsants (27%), and neuroleptic drugs (11%).
Antidepressant treatment was tricyclic/tetracyclic treatment almost exclusively. Anticonvulsants, in most cases carbamazepine, was mostly prescribed for patients with combined drug use or high-dose benzodiazepine addiction, who were significantly more often treated with anticonvulsants compared to low-dose addicted subjects.
Despite a negative recommendation according to AWMF-guidelines for medication addiction, low potential neuroleptic drugs were used frequently in all patient groups.
80% of included subjects had at least one comorbid psychiatric condition, before all depressive disorder, anxiety disorders, PTSD, and other adjustment disorders. 67% of patients described traumatic life-events. These were significantly more often found in high-dose compared to low dose benzodiazepine addicted patients. | de |
dc.contributor.coReferee | Meyer, Thomas Prof. Dr. | |
dc.subject.ger | Benzodiazepin | de |
dc.subject.ger | Opioidanalgetika | de |
dc.subject.ger | Nichtopioidanalgetika | de |
dc.subject.ger | Psychopharmakotherapie | de |
dc.subject.ger | stationäre | de |
dc.subject.ger | Medikamentenentzugsbehandlung | de |
dc.subject.ger | Entzug | de |
dc.subject.ger | Entzugsbehandlung | de |
dc.subject.eng | substance | de |
dc.subject.eng | opioid | de |
dc.subject.eng | addiction | de |
dc.subject.eng | benzodiazepine | de |
dc.subject.eng | non-benzodiazepine | de |
dc.subject.eng | abuse | de |
dc.subject.eng | non-opioid | de |
dc.subject.eng | withdrawal | de |
dc.subject.eng | psychopharmacotherapy | de |
dc.identifier.urn | urn:nbn:de:gbv:7-11858/00-1735-0000-002B-7C9E-1-5 | |
dc.affiliation.institute | Medizinische Fakultät | de |
dc.subject.gokfull | Medizin (PPN619874732) | de |
dc.description.embargoed | 2016-11-22 | |
dc.identifier.ppn | 872311821 | |