Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Göpfert, Martin Prof. Dr."
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Neuronal Circuit Dissection in the Drosophila Brain: the Role of Serotonin-Releasing Neurons in Arousal
(2014-08-18)For animals, an optimal arousal state is essential for motivating or inhibiting a specific behavior. Arousal is regarded to be an internal factor that influences the initiation and execution of different behaviors, and is ... -
Plasticity of Dopamine-Releasing Central Brain Neurons Underlying Adaptational Feeding-Related Behavior in Drosophila Melanogaster
(2020-05-07)All organisms have to adapt and adjust behaviors to changing environmental conditions. Foraging and feeding behaviors are one of the most adaptive behaviors when changes in nutrient sources occur. Neuronal and behavioral ... -
Role of mechanosensitive ion channels in coordinated epithelial cell dynamics in Drosophila
(2019-11-20)Epithelial cells are able to sense and mechanically respond to the forces and movements generated and transmitted through their neighbors. These forces are multicellular at the tissue level, and are transmitted via multimeric ... -
Sound Encoding in the Mouse Cochlea: Molecular Physiology and Optogenetic Stimulation
(2014-04-24)Afferent synapses between inner hair cells (IHCs) and spiral ganglion neurons in the cochlea translate sound information into a discrete spike code, providing us the opportunity to directly observe the output of the cochlea. ... -
Strategies for dynamic vision in the Drosophila peripheral visual system
(2022-04-21)Changes in luminance over space and time drive visual behaviors across species. Thus, sensitivity to luminance changes or contrast is fundamental to visual perception. Visual perception has to work in many different ... -
Structural determinants of voltage-dependent gating of Kv10.1
(2022-01-07)Voltage-gated ion channels sense voltage through the movement of the voltage sensor in response to change in membrane potential, hence influencing the channel pore. In this project, we seek a deeper understanding of ... -
Synaptic physiology of the cochlear sound encoding
(2013-11-27)Sound intensity is encoded as action potential firing rates by spiral ganglion neurons. These neurons show different rate-level functions with different auditory thresholds, and are thought to collectively encode the large ... -
Synaptic Ultrastructure and Regulation of Synaptic Transmission in Caenorhabditis elegans
(2012-11-07)The triggered release of synaptic vesicles (SVs) is tightly regulated in time and space by an elaborate network of proteins forming the active zone (AZ). When visualized by electron microscopy (EM), a morphological hallmark ... -
The role of attention and adaptation in shaping cortical representations and the perception of abrupt changes in the visual environment
(2017-11-22)The visual system receives a wealth of visual information about objects with changing features in time. Attention is a mechanism allowing us to prioritize the processing of relevant information at the expense of other ... -
Thermosensory Transduction Mechanisms in Drosophila melanogaster
(2019-10-18)Ambient temperature has an profound effect in the physiology of all animals and accurate evaluation of both external and internal temperatures is therefore an essential factor for fitness and survival. To this end, animals ... -
Touch comes of Age - Maturational Plasticity in Somatosensory Mechanosensation
(2020-08-06)Somatosensory mechanosensation remains to be the least understood sensory system in vertebrates. It requires the activation of specialised neurons which innervate the skin and internal organs. A subset of these dorsal root ... -
Touching upon regulators of Piezo2 in mouse somatosensation
(2018-03-15)ABSTRACT Mechanosensation is an integral property of sensory systems like audition and somatosensation. The molecular determinants of mechanotransduction in mammals are only beginning to be understood. In 2010, Piezo2, a ...