Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Göpfert, Martin Prof. Dr."
Now showing items 1-8 of 8
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Thermosensory Transduction Mechanisms in Drosophila melanogaster
(2019-10-18)Ambient temperature has an profound effect in the physiology of all animals and accurate evaluation of both external and internal temperatures is therefore an essential factor for fitness and survival. To this end, animals ... -
Linking senses: the genetics of Drosophila larval chordotonal organs
(2018-08-06)Sensory systems have evolved in all organisms to detect changes in the environment or their internal state. Even though they are essential for fitness and survival, their phylogenisis is still unclear. The protosensory ... -
Analyzing receptor responses in the Drosophila Johnston's organ with two-photon microscopy
(2017-07-31)Hearing organs rely on force-gated ion channels to convert the mechanical energy imposed by sound into receptor potentials usable by the nervous system. So far, little is known about the identity and working mechanisms of ... -
Probing roles of TRPML in Drosophila hearing
(2016-01-15)Several transient receptor potential (TRP) channels have been implicated in Drosophila hearing, including the TRPN channel NOMPC, the TRPVs Nan and Iav, and the TRPA members Pyx and Pain. Here I report that fly hearing ... -
Axonemal dyneins and force generation by neurons in Drosophila melanogaster ear
(2014-05-26)Analogous to vertebrate hair cells, the mechanosensory cilia of Drosophila auditory neurons are motile and serve dual, transducing and actuating roles. Structurally, the latter cilia resemble non-motile primary cilia, ... -
Gene Ontology-based framework to annotate genes of hearing
(2013-10-22)As the number of discovered deafness genes and our knowledge about their role in hearing continuously increases, the need to accurately manage this genetic information is becoming more apparent. Gene Ontology (GO) is a ... -
Genetics of Drosophila hearing
(2013-10-04)By probing Johnston’s organ function in mutant fly strains, mutations in forty-four genes that affect Drosophila hearing have been identified. This result increases the list of genes that are known for audition by 180 % ... -
A Functional Characterisation of Drosophila Chordotonal Organs
(2013-06-27)Functional properties of the Drosophila FCO (femoral chordotonal organ) can be dissected by use of the Gal4-UAS system in combination with transcuticular in vivo Calcium imaging. As sinusoidal stimulation at relative ...