Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Advisor "Schu, Peter Prof. Dr."
Now showing items 1-4 of 4
-
Mechanisms of synaptic plasticity mediated by Clathrin Adaptor-protein complexes 1 and 2 in mice
(2019-06-13)Clathrin adaptor protein complexes 1 and 2 (AP1 and AP2) have essential functions in synaptic vesicle (SV) recycling. In all cell types and tissues, AP1 mediates TGN/endosome protein sorting via clathrin-coated-vesicles ... -
Modifications in AP2 and clathrin-mediated endocytosis as a mechanism of synaptic plasticity
(2022-07-01)AP2 CME fulfills essential functions in embryonic development and cell survival. The AP2 complex and clathrin form AP2 CCV together with sixty other coat proteins. Due to this complex protein network, the regulation of CCV ... -
Synaptic vesicles dynamics in σ1B adaptin -/- mouse model
(2015-07-20)The adaptor protein 1 (AP-1) complex of clathrin-coated vesicles (CCVs) mediates protein transport between the trans-Golgi-network and endosomes. It consists of the two large adaptins γ1 and β1, both of which bind clathrin ... -
Das synaptische Vesikelrecycling: Molekulare Funktionen des AP-1-Komplexes und seiner σ1B-Adaptinuntereinheit
(2012-09-26)The heterotetrameric AP-1-complex is localized to trans-Golgi-Network (TGN) and early endosomes. It mediates specific clathrin-dependant vesicular pathways. In vertebrates three isoforms of its σ1 subunit are expressed: ...