Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Bastians, Holger Prof. Dr."
Now showing items 1-5 of 5
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Mechanics and Motility of Epithelial Cells: From Single Cell Behavior to Collective Migration
(2023-01-13)Mechanical behavior of cells plays a crucial role in a plethora of biological processes. Despite its importance, this aspect of life science has only more recently gained increasing interest. Yet, without mechanical force ... -
Investigation of the role of microtubule dynamics in paracrine signaling and cell invasion in human cancer cells
(2021-09-23)Metastasis is a critical characteristic of aggressive human cancer, which is determined by the acquirement of increased cancer cell migration and invasion capabilities. Recent published work indicated that supernumerary ... -
Regulation Of Spindle Orientation By A Mitotic Actin Pathway In Chromosomally Unstable Cancer Cells
(2020-11-18)Aneuploidy is a hallmark of human cancer and is observed in 90 % of solid tumors. The perpetual gain or loss of whole chromosomes, defined as chromosomal instability (CIN), represent one mechanism causing aneuploidy. CIN ... -
A Role For Microtubule Dynamics For The Induction Of Chromosomal Instability And Cell Migration And Invasion In Human Cancer Cells
(2017-06-21)Aneuploidy and increased cell migration and invasion are hallmarks of aggressive human cancers. Aneuploidy derives from an increased rate of perpetual chromosome missegregation during mitosis, referred to as chromosomal ... -
The role of LEF1 and WNT signaling in growth and differentiation of rhabdomyosarcoma
(2017-02-16)Rhabdomyosarcoma (RMS) is the most common type of soft tissue sarcoma in children and shows characteristics of skeletal muscle differentiation. RMS occur in two main histological subtypes in children: alveolar RMS (ARMS) ...