Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Lüder, Carsten Prof. Dr."
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Identification of factors involved in cell wall homeostasis and tolerance towards quaternary ammonium compounds in Listeria monocytogenes by genomic adaptation
(2023-06-20)Listeria monocytogenes is one of the most successful food-borne pathogens worldwide. Despite available treatment with cell wall targeting antibiotics an infection with concomitant development of listeriosis results in death ... -
Protein Interactions in minimal cells
(2022-05-18)Minimal cells are used to model and understand life’s complex processes. The most essential processes of life are thought to include cell replication, energy metabolism and genome maintenance. However, construction of a ... -
A protein in search of a function: The c-di-AMP-binding protein DarA of Bacillus subtilis
(2019-07-26)Adaptation to changing environmental conditions is crucial for any organism to thrive in nature. Bacteria like the Gram-positive model organism Bacillus subtilis have evolved so-called second messengers to facilitate ... -
Identification of essential and virulence genes in Mycoplasma pneumoniae
(2019-04-16)The bacterial group of Firmicutes includes many pathogenic bacteria, as Mycoplasma pneumoniae. The Gram-positive, but cel wall-less bacterium is characterized by a minimal genome with only 694 genes. Elucidating the function ... -
Cyclic di-AMP homeostasis and osmoregulation in Listeria monocytogenes
(2019-04-05)The second messenger cyclic diadenosine monophosphate (c-di-AMP) is essential for most of the bacteria synthesizing the nucleotide. c-di-AMP is produced by diadenylate cyclases (DACs) and degraded by specific phosphodiesterases ... -
Vitamin B6 Production in Bacillus subtilis
(2018-01-23)Fermentative production of valuable goods is an economically competitive and ecologically sustainable alternative to chemical synthesis. Several previous studies have been dedicated to the establishment of vitamin B6 ...