Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Lenart, Peter Dr."

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    • Cytoskeletal networks in living cells under strain 

      Meyer, Ruth (2025-07-15)
      The eukaryotic cytoskeleton consists of three types of filamentous proteins: actin filaments, microtubules and intermediate filaments (IFs). In contrast to actin and tubulin, IF proteins are expressed in a cell-type specific ...

    • Mechanisms of chromosome segregation in mammalian oocytes 

      Saha, Debojit (2024-12-10)
      Errors in chromosome segregation in human females often result in eggs with the wrong number of chromosomes, a condition known as aneuploidy. The rate of aneuploidy increases dramatically in women with age, particularly ...

    • Interplay of proteins and lipids during endoplasmic reticulum-associated protein degradation 

      Vrentzou, Aikaterini (2024-11-14)
      The endoplasmic reticulum controls lipid homeostasis due to its central role in lipid biosynthesis and its regulation. Aberrant lipid composition and membrane properties in the endoplasmic reticulum interfere with its ...

    • Interactions between cytoskeletal filaments in cells 

      Blob, Anna Friederike (2024-10-04)
      Essential functions of eukaryotic cells such as cell division, force generation and the ability to mechanically adapt to the outer environment depend on the cytoskeleton, which is an intricate network containing three ...

    • Mechanisms underlying age-related decline in mammalian female fertility 

      Sharma, Ninadini (2024-03-05)
      Reproductive longevity is crucial for fertility and impacts healthy ageing. Unlike in men, fertility in women starts to decline several decades before other signs of ageing set in. Female fertility is restricted by a limited ...

    • Functions of cytoplasmic lattices in mammalian oocytes and embryos 

      Jentoft, Ida Marie Astad (2023-12-12)
      Preimplantation embryogenesis is dependent on maternally stored proteins, transcripts, and other macromolecules. Although this is a well-established dogma, it is unclear how mammalian oocytes store maternal factors needed ...

    • Investigating phase separation mechanisms for transcriptional control 

      Böhning, Marc (2020-11-13)
      Transcription of protein-coding genes by RNA polymerase (Pol) II is a highly coordinated process. In metazoan cells, transcription is regulated both at the initiation step by recruitment of the Pol II machinery as well as ...

    • Mechanisms of pronuclear migration in mammalian zygotes 

      Uraji, Julia (2019-08-30)
      In sexually reproducing species, life begins with the fusion of egg and sperm to form the one-cell embryo, called the zygote. Maternal and paternal DNA form the female and male pronuclei, and must migrate to each other to ...