Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Schu, Peter Prof. Dr."
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Mechanisms of synaptic plasticity mediated by Clathrin Adaptor-protein complexes 1 and 2 in mice
(2019-06-13)Clathrin adaptor protein complexes 1 and 2 (AP1 and AP2) have essential functions in synaptic vesicle (SV) recycling. In all cell types and tissues, AP1 mediates TGN/endosome protein sorting via clathrin-coated-vesicles ... -
Synaptic vesicles dynamics in σ1B adaptin -/- mouse model
(2015-07-20)The adaptor protein 1 (AP-1) complex of clathrin-coated vesicles (CCVs) mediates protein transport between the trans-Golgi-network and endosomes. It consists of the two large adaptins γ1 and β1, both of which bind clathrin ... -
Das synaptische Vesikelrecycling: Molekulare Funktionen des AP-1-Komplexes und seiner σ1B-Adaptinuntereinheit
(2012-09-26)The heterotetrameric AP-1-complex is localized to trans-Golgi-Network (TGN) and early endosomes. It mediates specific clathrin-dependant vesicular pathways. In vertebrates three isoforms of its σ1 subunit are expressed: ...