Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Stoykova, Anastassia Prof. Dr."
Now showing items 1-6 of 6
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Cortical patterning and neuronal migration are under the guide of BAF complex functionality
(2020-03-26)The brain is one of the complex organs designed under the control of a plethora of molecular and cellular regulatory mechanisms, including transcriptional and epigenetic pathways. Brain organogenesis proceeds in a stepwise ... -
Functional analysis of the parkinsonism-associated protein FBXO7 (PARK15) in neurons
(2017-09-07)Parkinson's disease (PD) is a debilitating neurodegenerative disease affecting the elderly population. It has been a challenge elucidating the molecular mechanisms underlying the selective loss of dopaminergic neurons, ... -
Pancreatic β-Cell Regeneration in TIF-IA Knockout Mice
(2014-09-30)As the sole source of insulin production in body, pancreatic β-cells play an essential role in glucose homeostasis. Diabetes mellitus is a chronic disease characterized by loss, reduction, and/or malfunction of β-cell mass. ... -
Characterization of the CNS-specific F-box protein FBXO41 in cerebellar development
(2014-05-28)During neurodevelopment, processes like neurogenesis, neuronal migration and morphogenesis, as well as synaptogenesis determine the shape and function of the brain. All developmental events are highly coordinated by extrinsic ... -
Transcription factor Pax6 controls structure and function of the centrosome in cortical progenitors
(2013-07-15)The mammalian neocortex is a highly complex structure containing more than 100 billions neurons and ten times more glia cells that are generated during development by progenitor cells located at the apical surface of the ... -
Modulation of synaptic transmission by the voltage-gated potassium channel Eag1
(2012-06-18)The voltage-gated potassium channel Kv10.1 is widely expressed in the mammalian brain, but its function has not been described. Previous studies revealed highest expression levels in hippocampus and cerebellum and suggested ...