Dokumente Human- und Zahnmedizin nach Gutachter "Dobbelstein, Matthias Prof. Dr."
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The Necessity of Geminin for Pluripotency and Neural Lineage
(2013-08-21)Pluripotent mouse embryonic stem cells (ESCs) are in vitro derivatives of the early mouse embryo. They can self-renew infinitely, and have the ability to differentiate into embryonic lineages including the germ line. ESCs ... -
Der Tumorsuppressor p53 reguliert HSF1 im Modell des kolorektalen Karzinoms
(2021-07-13)The regulator of the cellular stress response programm HSF1 is regulated by the tumor suppressor p53 by inhibition of the phosphorylation of Ser326. This reduces HSF1 transcriptional activity and halts the stress response ... -
Untersuchungen zur Regulation der Zelladhäsion durch PHD2 in Tumorzellen
(2012-07-24)The hypoxia-inducible factor 1 (HIF-1) is a transcription factor, which is stabilized under hypoxic conditions. It consists of the HIF-1β- as well as of one of three known HIF-α-subunits. One of its