Browsing Human- und Zahnmedizin by Referee "Burckhardt, Birgitta-Christina Prof. Dr."
Now showing items 1-9 of 9
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Die pH-Abhängigkeit des NaDC3-Transporters
(2017-11-27)The sodium-dependent dicarboxylate transporter 3 (NaDC3) is located close to organic anion transporters (OAT) in the basolateral membrane of renal proximal tubule cells. The transport-activity of OAT1 (p-aminohippurate) ... -
Interaktion des NaDC3 und des NaCT mit Carbaglu, einem Medikament zur Behandlung der Hyperammonämie
(2017-10-27)Primary or secondary N-acetylglutamate synthase (NAGS) deficiency leads to the reduction of N-acetylglutamate (NAG), the natural activator of the urea cycle. It results in hyperammonemia. Hyperammonemic crises can be ... -
Untersuchung der Transportvorgänge des Prolyl-Hydroxylase-Hemmers ICA an den Transportern OAT1, OAT2, OAT3 und OAT4 von proximalen Nierentubuluszellen
(2017-10-27)This thesis discusses the interactions between ICA and the organic anion transporters OAT1, OAT2, OAT3 and OAT4. ICA is a substance which can inhibit the prolyl hydroxylase domain. This leads to an upregulation of hypoxia ... -
Einflüsse der Serum- und Glukokortikoidkinasen 1 und 3 auf den humanen Na⁺- Dikarboxylat- Transporter NaDC3
(2017-08-15)NaDC3 is responsible for the uptake of dicarboxylates necessary for the organic anion-dicarboxylate exchange via the organic anion transporters 1 and 3 (OAT1 and 3) that contribute to renal excretion. It is assumed that ... -
Anwendung von Notfallbeatmungsgeräten zur invasiven und nicht-invasiven Beatmung an einem Versuchsmodell - resultierende Beatmungsgrößen und gastrale Insufflation
(2015-06-16)Background: Respiratory insufficiency and therapy are central problems in emergency and critical care medicine. If ventilation is necessary, a possible treatment could be invasive (e.g. via tracheal tube) or non-invasive ... -
Bestimmung von Prognosemarkern unter nephroprotektiver Therapie mit ACE-Hemmern bei chronischer Nierenfibrose am Beispiel des Alport-Syndroms
(2013-11-26)Firstly described in 1927, Alport syndrome is a progressive hereditary nephropathy. Untreated, it leads to end-stage renal failure and is associated with the symptoms of hematuria and proteinuria. The aim of this work was ... -
Evaluation eines neuartigen Beatmungshelms zur nicht-invasiven Beatmung (NIV) anhand einer Probandenstudie und anhand eines Lungenmodells zur Simulation obstruktiver und restriktiver Ventilationsstörungen
(2013-05-13)Ventilation has a significant value in the therapy of acute respiratory failure. Since invasive ventilation via an endotracheal tube always involves risks, a non-invasive ventilation should be applied whenever possible. ... -
Erkennung diagnostischer Frühmarker der Nierenfibrose beim Tiermodell des Alport-Syndroms mittels proteomischer Methoden
(2013-03-05)Alport syndrome is a progressive, hereditary nephropathy which is characterized by typical changes in the basement membrane leading to proteinuria and hematuria. Proteines, which then pass the glomerular filter, occurring ... -
Lungenfunktionsuntersuchungen bei Patienten mit Myasthenia gravis pseudoparalytica
(2011-02-03)Myasthenia gravis is an autoimmune disease characterised by exercise-induced muscular weakness. If the respiratory muscles become affected, the patient is at risk for a myasthenic crisis ...