Dokumente Human- und Zahnmedizin nach Gutachter "Siggelkow, Heide Prof. Dr."
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Die Wirkungen der Fraktionen bzw. Subfraktionen des Extraktes Cimcifuga racemosa BNO 1055 auf Uterus und Vagina der Ratte
(2023-10-27)The search for herbal alternatives to classic hormone replacement therapy has recently played an increasingly important role. Pharmaceuticals - which are used as alternatives to classic hormone replacement therapy for the ... -
Die Auswirkung vom 5- Lipoxygenaseinhibitor Zileuton auf osteoporotische Wirbelkörper im Rattenmodell
(2023-04-11)According to the World Health Organization, osteoporosis is one of the ten most common diseases in postmenopausal women over the age of 50. In addition to the lack of estrogen in the postmenopause, the influence of the ... -
Schwere Osteoporose unklarer Genese- Ergebnisse intensiver Diagnostik, inklusive Knochenbiopsie und Genetik
(2023-01-31)Schwere Osteoporose unklarer Genese - Ergebnisse intensiver Diagnostik einschließlich Knochenbiopsien und molekulargenetische Untersuchungen Einleitung: Bei manchen Betroffenen mit schwerer Osteoporose wird mittels ... -
Analyse der RANKL-Inhibition durch Virus-like Partikel vermittelte RNA-Interferenz im Osteoporose-Modell der Ratte
(2022-04-14)Postmenopausal osteoporosis is an underestimated, widespread disease. Due to demographic trends, the prevalence of osteoporosis will further increase in the next decades.The treatment of postmenopausal osteoporosis is still ... -
Charakterisierung der Knochendichte im Bereich der Wirbelsäule mittels quantitativer Computertomographie
(2022-03-21)Purpose Pedicle Screw loosening is one major problem in posterior instrumentation especially in patients with osteoporosis. Augmentation of pedicle srews with cement is a common procedure to improve the stability of the ... -
Therapiemöglichkeiten zur metaphysären Frakturheilung am männlichen, osteoporotischen Rattenmodell
(2022-03-08)Osteoporosis and osteoporotic fractures make up a large proportion of diseases of the elderly. While osteoporosis in women is researched fairly well and targeted by a variety of therapeutic drugs, the disease has long been ... -
Frakturrisikoevaluation mithilfe verschiedener nationaler und internationaler Risikoscores bei Frauen
(2021-11-02)In the management of osteoporosis the determination of fracture risk is essential for the indication of a specific antiosteoporotic treatment. Within Europe different scores are used for fracture risk prediction. We used ... -
Die Rolle von Arlts1 im Glioblastoma multiforme
(2020-06-18)Determination of specific Glioblastoma (GBM) biomarkers could be beneficial in developing new therapeutics, monitoring the response to therapy or for early detection of recurrence. Downregulation and tumor suppressor effect ... -
Die Wirkung von Vitamin D in Kombination mit Ecdyson und Östrogen auf Uterus und Mamma der ovarekomierten Ratte
(2019-07-03)In an ageing society, a growing number of female patients is affected by climacteric symptoms. Therapeutic options include long established treatments like hormone replacement therapy (HRT) and substitution of vitamin D ... -
Versorgungsschwerpunkte der Frauen mit UTS - Zusammenstellung der Daten aus fünf verschiedenen Endokrinoliogika
(2019-03-12)Introduction: The Ullrich-Turner-Syndrome (UTS) is caused by the complete or partial absence of the second X-chromosome and associated with multiple comorbidities. Dwarfism (average 20 cm smaller than normal) and delayed ... -
Gewinnung und Charakterisierung von osteoblastären Zellen aus dem humanen Alveolarknochen
(2018-05-14)Osteoblasts represent one of the most important cell groups for bone forming as well as bone structuring and involve essentialy, together with osteoclasts and osteocytes, in the bone metabolism. Their main task, the secretion ... -
Gewinnung und Charakterisierung von humanen Zementoblasten
(2018-05-14)Root cementum represents one of the crucial prerequisites for an intact fixation in the tooth's osseous socket, the alveole. Healthy cementum and its self-repair mechanisms are furthermore vital to a sound parodontium and ... -
Die Wirkung von Ecdyson und Vitamin D auf Knochen-, Muskel- und Fettgewebe bei der ovariektomierten Ratte, bestimmt mittels quantitativer Computertomographie
(2018-02-21)Ecdysone (Ecd) demonstrated muscle anabolic, antiosteoporotic and antilipotropic properties in ovariectomized (ovx) rats in multiple trails. But its mechanism af action in mammalia has not been understood until yet. Because ... -
Antagonisiert ein ER β-Agonist die Wirkung von ER α im Fett- und Muskelgewebe der ovarektomierten Ratte?
(2018-02-21)In this study we analyzed the effect of ER α 16α-LE2 (3,17-dihydroxy-19-nor-17α-pregna-1, 3,5(10)-triene-21, 16α-lacton) and ER β 8β-VES (8-vinylestra-1, 3,5(10)-triene-3,17β-diol)-Agonist as well as the sex hormone E2 ... -
Bisphosphonat-assoziierte Osteonekrosen der Kiefer - Eine retrospektive Studie unter besonderer Berücksichtigung der Lebensqualität
(2017-09-14)The cause of bisphosphonate-associated osteonecrosis of the jaw is yet to be determined. The intention of the study was to clarify the question to what extent quality of life will be limited by osteonecrosis. Furthermore, ... -
Metabolisches Syndrom: Die Effekte von 20-Hydroxyecdyson und 17β-Östradiol auf den Knochen und die Muskulatur der ovarektomierten Ratte
(2017-07-12)Effects on musculature and bone were shown in ovariectomized rats after 4 weeks application of ecdysone and estradiol. -
Der Effekt der pränatalen Dexamethasontherapie auf die Fettparameter der Nachkommen beim Callithrix jacchus
(2017-03-02)The aim of the present work was to investigate whether a prenatal dexamethasone therapy in the first and / or second trimester of pregnancy leads to certain metabolic changes in the male offspring. The test animals were ... -
Steroid-responsive Enzephalopathie bei Autoimmunthyreoiditis als Differentialdiagnose der Creutzfeldt-Jakob-Krankheit
(2016-03-08)The SREAT is a rare, progressive multiform disease that is not well understood. It is characterized by wide unspecific neuropsychiatric symptoms, elevated thyroid antibodies, and the good response to immunosuppressive ... -
Metabolisches Syndrom: Die Effekte von 20-Hydroxyecdyson und 17-beta-Östradiol auf das Fettgewebe und die subkutane Körpertemperatur der ovariektomierten Ratte
(2014-12-08)Effects of visceral body fat were shown in ovariectomized rats after 4 weeks application of ecdysone. Reduction of mean body temperature has been proved after 1 week of ecdysone- application in ovariectomized rats. -
Der Einfluss des Transkriptionsfaktors Runx2 auf osteogene und adipogene Differenzierungsmarker, insbesondere auf PPARγ
(2014-01-07)Mesenchymal stem cells can differentiate into osteoblasts, adipocytes, chondrocytes or myoblasts depending on the predominant transcription factor. The influence of Runt-related transcription factor 2 (Runx2) increases ...