Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Braus, Gerhard Prof. Dr."
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Charakterisierung des mRNA-Exportweges bei zellulärem Stress in Saccharomyces cerevisiae
(2016-11-15)In response to stress cells activate a prompt expression of stress-specific genes of which chaperones are essential in stabilizing and refolding proteins. In this situation stress-specific RNAs are selectively transcribed, ... -
Charakterisierung eines Proteinkomplexes in Säugerzellen, der am Transport zwischen Membrankompartimenten beteiligt ist.
(2006-03-29)The intracellular trafficking allows dynamic flux of proteins and lipids between different compartments. This is largely mediated by the budding of vesicles from a donor compartment, followed ... -
Chararcterisation of fungal protein kinases involved in the regulation of the cell cycle of Saccharomyces cerevisiae and of sexual development in Aspergillus nidulans
(2007-11-22)In this work, fungal model organisms, the single cell budding yeast Saccharomyces cerevisiae and the filamentous fungus Aspergillus nidulans were used to characterize different factors ... -
Chromatinstruktur und Regulation der Genexpression am Histidin/Adenin-Verzweigungspunkt in Hefe und Aspergillus
(2001-10-23)Imidazole glycerole phosphate (IGP) synthase (E.C.2.4.2. & E.C.4.3.2.4) catalyzes the fifth and the sixth reaction step of the histidine biosynthesis. The byproduct of the reactions, AICAR, ... -
Cross-Pathway Control of the Pathogenic Fungus <i>Aspergillus fumigatus</i>: a Manifold Stress Response System
(2008-11-10)In this study the Cross-Pathway Control (CPC) of the opportunistic pathogenic fungus Aspergillus fumigatus was analysed in view of putative stress response genes, which enables the fungus ... -
Cyclic monophosphate cyclase in Firmicutes: from basic to practical approach
(2019-01-30)Cyclic di-adenosine monophosphate (c-di-AMP) is a second messenger involved in diverse metabolic processes such as cell wall homeostasis, biofilm formation, antibiotic and heat resistance, among others. In Lactococcus ... -
DAHP Synthasen aus Pilzen
(2002-07-09)The first step of the biosynthesis of the aromatic amino acids is the condensation of erythrose-4-phosphate and phosphoenolpyruvate to 3-deoxy-D-arabino-heptuloso-nate 7-phosphate. This ... -
Deneddylation and fungal development - Regulation of Nedd8 protein modification by DenA and the COP9 signalosome
(2012-08-16)Ubiquitin dependent protein degradation is a common principle in eukaryotic organisms to control appropriate temporal and spatial protein levels. Abnormal regulation leads to embryonic lethality in plants, insects and ... -
Developmental regulators and secreted effector molecules of the fungal pathogen Verticillium spp.
(2020-09-29)The haploid Verticillium dahliae and the allodiploid V. longisporum are two filamentous fungal pathogens, which colonize the plant vascular system of a broad host range including important crops. They survive outside of ... -
DNA methylation as a potential epigenetic driver of morphological development in Candida albicans
(2022-01-04)Candida albicans is a commensal yeast in the mammalian gut, but also has retained its virulence potential while co-evolving in mammalian species. As a perfectly adapted opportunist colonizing mucosal surfaces, it is also ... -
Epidemiologische Untersuchungen zur Toxoplasmose und Identifizierung immunogener parasitärer Antigene
(2012-02-23)Toxoplasmosis is an infectious disease caused by the parasite Toxoplasma gondii. Whereas the infection proceeds in most cases asymptomatically in immunocompetent humans, a threat for the ... -
Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes in late cortical development and beyond
(2019-08-29)The multi-subunit BAF (SWI/SNF) complex is capable of using energy generated from ATP hydrolysis to reorder chromatin structure. Such chromatin changes are known to affect cell biological processes through gene expression ... -
Etablierung eines Nachweisverfahrens zur Untersuchung der räumlichen und zeitlichen Verteilung mitochondrial translatierter Proteine mit hochauflösender STED-Mikroskopie durch metabolische Markierung mit nicht-kanonischen Aminosäuren
(2017-09-14)Metabolic labeling of nascent polypeptides using non-canonical amino acids is a valuable tool enabling researchers to introduce bioorthogonal functional groups into proteins. These can subsequentially be used for identifying ... -
Expression, Charakterisierung und Kristallisation der spleißosomalen Proteine SMNrp, U4/U6-60k und U4/U6-90k
(2006-01-20)The U4/U6-20k/60k/90k-complex, a component of the U4/U6*U5-snRNP-complex, and SMNrp are involved in the assembly of the human spliceosome. It was suggested that the recruiting of the ... -
Fettsäuretransport in die peroxisomale Matrix von <i>Arabidopsis thaliana</i>
(2007-08-15)Fatty acids are essential components of living organism. The distribution of fatty acids between cells as well as within a cell is a complex process due to their low solubility in water. ... -
Functional analysis of STRIPAK complex components in the filamentous ascomycete Sordaria macrospora
(2018-08-09)The striatin-interacting phosphatase and kinase (STRIPAK) complex is conserved in fungi and animals. The STRIPAK in the filamentous ascomycete Sordaria macrospora, was previously found to be essential for hyphal fusion and ... -
Functional characterization of the human renal organic anion transporter 3 (hOAT3) and comparison to hOAT1
(2004-06-01)Renal secretion of organic anions is critically dependent on their basolateral uptake against the electrochemical gradient. Due to their localization, two transporters are likely involved, ... -
Germ cell development and migration
(2005-07-29)Sexually reproducing organisms arise from gametes (sperm and egg), which develop from primordial germ cells (PGCs), a small population of cells that set aside from other cell lineages ... -
Governing fungal polar cell extension: Analysis of Rho GTPase and NDR kinase signalling in Neurospora crassa
(2008-05-16)Polar morphogenesis is required for the function of elongated cell types like neuronal cells, pollen tubes and cells of filamentous fungi. The basal signalling components involved are highly conserved. Defects in polar ... -
Guanylatkinase: Von einem aktiven Enzym zu einem inaktiven Multidomänen-Protein.
(2001-06-14)Guanylate kinase (GUK) is an essential enzyme for nucleotide metabolism and catalyses the reversible transfer of the terminal phosphoryl group from Mg×(d)ATP to (d)GMP. Although the catalytic ...