Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Heinrich, Ralf Prof. Dr."
Now showing items 1-14 of 14
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Anti-apoptotic and neuroprotective erythropoietin/CRLF3-signalling in insects and humans
(2022-06-14)The cytokine receptor like factor 3 (CRLF3) evolved together with the eumetazoan nervous system and is present in all major groups of Animalia. Based on sequence similarities, CRLF3 was assigned to the family of class 1 ... -
Functional characterization and molecular identification of neuroprotective receptors for erythropoietin-like ligands
(2019-12-19)The cytokine erythropoietin (Epo) regulates erythropoiesis but also protects mammalian neurons from apoptosis. However, receptors and transduction pathways involved in neuroprotection are only partially characterized. ... -
Erythropoietin-mediated neuroprotection in insects
(2016-08-30)The cytokine erythropoietin (Epo) initiates adaptive cellular responses to a variety of mechanical and physiological insults in various non-hematopoietic mammalian tissues including the nervous system. Previous studies on ... -
Molecular mechanisms of acute axonal degeneration in the rat optic nerve
(2015-12-03)The development of neuroprotective treatments is urgently needed for neurodegenerative and neurotraumatic diseases. As axonal degeneration is a key initiating event in these diseases, it is pivotal to better understand and ... -
Regulation of Dual Leucine Zipper Kinase (DLK) by Prediabetic Signals
(2013-11-01)Diabetes mellitus type 2 is the most increasing metabolic disease worldwide. The disease is recognized by the disability of endocrine pancreas to afford the high metabolic demand which has been raised due to insulin ... -
Modulatorische Effekte von Stickstoffmonoxid und Juvenilhormon auf die Kontrolle des Reproduktionsverhaltens in weiblichen Chorthippus biguttulus
(2010-11-26)Juvenile hormone (JH) and nitric oxide (NO) both influence the reproductive behavior of female grasshoppers. The present thesis explores a possible connection between JH and NO signaling ... -
Expression and function of erythropoietin and its receptor in invertebrate nervous systems
(2010-02-08)This doctoral study provided substantial evidences for the presence of the EPO/EPOR signalling system in the CNS of invertebrates from different phyla (chapter 2) and demonstrated neuroprotective ... -
Die Bedeutung der Proteine 4.1G und 4.1N für den Aufbau und die Funktion glutamaterger Synapsen
(2009-09-14)In the present study, the role of proteins 4.1G and 4.1N for the synaptic localisation of AMPA receptors and neurotransmission at glutamatergic synapses in the mouse brain has been examined. ... -
Untersuchungen zur Funktion des basischen Helix-Loop-Helix (bHLH)-Transkriptionsfaktors ME2 bei Lern- und Gedächtnisprozessen in der Maus
(2009-08-20)ME2 (Tcf4) belongs to the basic helix-loop-helix (bHLH) transcription factor family, activates transcription of target genes by binding to so-called E-boxes elements and its mRNA expression ... -
Possible Influences of Circadian Melatonin on the Function of Neurosecretory Neurons and Serotonin-Modulated Behavior on Crayfish.
(2009-01-15)Crustaceans have frequently been used to study the neuroethology of diverse function as agonistic behavior and circadian rhythms. Whether the highly stereotyped and quantifiable agonistic ... -
Gesangskontrolle durch Neurone des Zentralkomplexes: Physiologische und immunzytochemische Untersuchungen an primären Zellkulturen aus dem Feldheuschreckengehirn
(2008-08-20)Acridid grasshoppers communicate with specific song patterns in the context of attracting partners for reproduction, courting and agonistic behavior. When to sing and which song pattern ... -
Functional organisation of the central complex of the grasshopper <i>Chorthippus biguttulus</i> in relation to sound production
(2008-05-27)The central complex is a major control neuropile for the situation specific selection of sound pattern of grasshoppers. The current thesis tries to investigate the role of different neurotransmitter systems in this brain ... -
Bone Marrow Derived Adult Stem Cells: Characterization and Application in Cell Therapy
(2007-04-25)Due to their high plasticity, ES cells offer a great promise in regenerative medicine; however, the ethical and serious clinical problems limit their application. On the other hand, the ... -
Pharmacological studies on the contribution of the neuropeptide proctolin to the cephalic control of singing behavior in grasshopper Chorthippus biguttulus (L.1758)
(2004-11-25)Injections of proctolin into the protocerebrum can elicit species-specific stridulation in both male and female grasshoppers of the species Chorthippus biguttulus. The stimulated behavior ...