Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Neher, Erwin Prof. Dr."
Now showing items 1-9 of 9
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Study of synaptic vesicle cycling during exo- and endocytosis using optical approaches
(2012-09-25)In the central nervous system, communication between nerve cells mainly occurs at synapses via chemical neurotransmitters. Upon stimulation the transmitters are released by Ca2+-triggered exocytosis of synaptic vesicles ... -
Epac-mediated modulation of neurotransmitter release from cultured hippocampal neurons
(2008-07-15)cAMP regulates secretory processes through both protein kinase A (PKA)-independent and PKA-dependent signaling pathways. However, their relative contributions to fast neurotransmission are ... -
Stimulus-secretion coupling in pancreatic β-cells of healthy and diabetic rats in tissue slice preparation
(2006-07-04)A primary event in the development of type 2 diabetes is a decrease in the capacity of pancreatic β-cells to secrete insulin in response to glucose stimulation. The Goto Kakizaki (GK) ... -
Spatial and temporal aspects of PI(4,5)P<sub>2</sub> and SNAREs in exocytosis studied using isolated membrane sheets and capacitance measurements
(2006-02-09)Ca2+-triggered exocytosis is a highly regulated process and the proteinaceous machinery mediating and regulating it has been studied in detail over the last decade. However, the participation ... -
Analysis of two kinetically distinct components of transmitter release at a fast synapse of the mammalian central nervous system
(2006-01-06)Two kinetically distinct components of transmitter release have been observed in Ca2+ uncaging experiments at a CNS synapse in rats, and both release components showed a steep dependence ... -
Munc18 function in large dense-core vesicle exocytosis
(2005-03-23)Neurotransmitter and hormon release is based on Ca2+ dependent exocytosis. The sequential steps of exocytosis are executed by proteins and protein complexes. Formation of the SNARE complex ... -
The Regulatory Role of Syntaxin 1 N-terminal Conformation in Vesicle Priming and Exocytosis
(2004-12-16)During vesicle priming at the central synapse, Syntaxin 1, together with SNAP25 and Synaptobrevin, assemble into the synaptic SNARE complex. The formation of SNARE complex is thought to ... -
Investigation of Interactions between Homeodomain Proteins and DNA
(2004-09-10)In this work spectroscopic and transient-kinetic methods were applied to investigate homeodomain-DNA interactions. The analysis of intrinsic fluorescence and circular dichroism spectra of ... -
Charakterisierung von einer retrograden Modulation inhibitorischer synaptischer Transmission im Kleinhirn der Ratte
(2003-12-15)In recent years, a lot of interest has been given to retrograde modulatory mechanisms of synaptic transmission: in many regions of the central nervous system, substances released from ...