Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Schwienhorst, Andreas PD Dr."
Now showing items 1-4 of 4
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Funktionelle Charakterisierung bakterieller Histondeacetylase-ähnlicher Amidohydrolasen (HDAH)
(2005-12-05)Until today, there is only little information about posttranslational modifications, especially acetylation of polypeptides in procaryotes to find in the literature. This thesis tries to ... -
Entwicklung von Substraten und Inhibitoren pharmakologisch relevanter Proteintargets
(2005-11-14)Thrombin: A series of thrombin inhibitors were generated by using powerful computer-assisted multiparameter optimization process. The process was organized in design cycles, ... -
Entwicklung eines HTS-geeigneten Enzymtests für Histondeacetylasen zur Entwicklung von HDAC-Inhibitoren
(2004-09-27)During the past years the pivotal role of histone deacetylases (HDACs) in tumourgenesis was discovered. These enzymes then were quickly ranked as molecular targets by the pharmaceutical ... -
Untersuchungen zu Struktur-Funktionsbeziehungen in der tRNA-ähnlichen Struktur des Rüben-Gelbmosaik-Virus
(2004-04-16)The Turnip-Yellow-Mosaic-Virus (TYMV) is a (+)-strand RNA-virus which infects plants of the Brassicaceae family. Its genome of 6318 nucleotides (nt) length contains a tRNA-like ...