Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Wimmer, Ernst A. Prof. Dr."
Now showing items 1-17 of 17
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Development of a biotechnologically enhanced sterile insect technique to fight coleopteran pests
(2021-06-30)Tribolium castaneum commonly referred to as the Red Flour Beetle (RFB) belongs to the class Insecta and order Coleoptera, and it’s the best model organism for coleopterans. About 380,000 coleopteran species, constituting ... -
Identification and Characterization of Novel Genes involved in Quinone Synthesis in the Odoriferous Defensive Stink Glands of the Red Flour Beetle, Tribolium castaneum
(2021-05-26)Defense strategies are common in insects including Coleoptera, the largest animal taxon containing various types of beetles. Stink gland secretion of beetles is playing an important role in their defense against detrimental ... -
Development of Transgenic Sterile Insect Technique Strains for the Invasive Fruit Pest Drosophila suzukii
(2020-12-03)Globalization has contributed enormously to emergence and expansion of invasive pests. A recent example is the invasion in Europe and the USA by the cherry vinegar fly Drosophila suzukii. The pest has high potential to ... -
Comparative analysis of organ size, shape, and patterning in diverse species
(2017-01-12)For a long time, the scientific community was concerned with the question how different tissues grow and differentiate. Much work in this respect has been done on complex 3-Dimentional vertebrate model limb systems such ... -
Comprehensive Morphological and Transcriptomic Analysis of the Chemosensory System in the Red Flour Beetle, Tribolium castaneum
(2016-11-18)The red flour beetle, Tribolium castaneum is an emerging coleopteran model system and thus represents the largest insect order with several agricultural and forest pests. Despite the ecological and economic importance of ... -
Oxidative stress pathways in the pathogenesis of renal fibrosis
(2016-05-23)In the pathogenesis of renal fibrosis, oxidative stress (OS) enhances the production of reactive oxygen species (ROS) leading to sustained cell growth, inflammation, excessive tissue remodelling and accumulation, which ... -
Biology of odoriferous defensive stink glands of the red flour beetle Tribolium castaneum
(2015-09-15)Chemical warfare is a very common defense strategy in the insect world. A broad range of coleopteran beetles react to predators, invaders, and parasitic microbes with the release of toxic and repellent substances, which ... -
Systematic Reverse Genetic Screen to Identify Novel Genes Required for Anterior Patterning of the Red Flour Beetle Tribolium castaneum
(2014-08-19)The formation of two main body axis is a crucial event during bilaterian de-velopment and has been in the focus of research for many years. The vinegar fly Drosophila melanogaster served as an excellent model organism for ... -
Biotechnological approaches to fight fruit flies of agricultural importance
(2012-10-08)Tephritid fruit flies destroy fruits and vegetables, causing tremendous economic losses and bringing a barrier to trade in fruits, vegetables and their associated products. The Sterile Insect Technique (SIT), a target-specific ... -
Funktionelle Analyse des Transkriptionsfaktors Uncx4.1 im murinen Mittelhirn
(2012-05-18)The development of the brain is a complex process, which involves a lot of finely regulated processes. The best known disease which is associated with the midbrain is morbus parkinson. In the last years a lot of effort was ... -
Funktionelle Charakterisierung der Transkriptionsfaktoren Nkx2.2 und Arx in der Entwicklung der endokrinen Zellen im murinen Pankreas
(2011-09-08)The pancreas is a compound-gland structured into two functional units exhibiting exocrine and endocrine properties. Exocrine cells produce and secret digestive enzymes, whereas endocrine ... -
Molecular Studies on Head Development of the Amphipod Crustacean Parhyale hawaiensis
(2011-08-09)The adult head of bilateral-symmetric animals is an anterior, usually tagmatised morphological unit. In segmented phyla, the development of the anterior head segments underlies different ... -
Regulation of segment polarity genes in the head region of different arthropods
(2010-10-11)Head segmentation in insects, as reflected by the model system Drosophila melanogaster, is less well understood in comparison to the trunk. While the gnathal segments (mandibular, maxillary, ... -
Anti-TGF-beta-Antikörper und Öffnung der Blut-Hirn-Schranke - Evaluation neuer Optionen zur Behandlung hochmaligner Gliome im Tiermodell
(2010-06-16)Malignant brain tumors are characterized by a very poor prognosis with current standard-of-care therapies. Even high dose chemotherapy and new experimental drugs have not improved the outcome ... -
Evolution of Sp Transcription Factors in Metazoans
(2010-02-09)In contrast to the well-known trunk segmentation mechanisms in the fruit fly Drosophila melanogaster the mechanisms of arthropod head segmentation are less well understood. While the ... -
New molecular technologies to improve the Sterile Insect Technique for the Mediterranean fruitfly <i>Ceratitis capitata</i> (Diptera; Tephritidae)
(2008-05-26)Insect pests cause enormous economic losses to livestock as well as pre- and postharvest stages of agricultural commodities. The Mediterranean fruit fly Ceratitis capitata (medfly; Wiedemann, Diptera: Tephritidae;) is one ... -
Downstream targets of transcription factor Pax6 in cortical development
(2008-04-22)Pax6 is a transcription factor with key functional roles in patterning and arealization of the cortex. We studied regulation of gene expression in Pax6 mutants through microarray analysis. This allowed us to focus on ...