Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Wimmer, Ernst A. Prof. Dr."
Now showing items 1-20 of 94
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Computational analysis of transcriptional regulation and chromatin assembly
(2023-12-07)Primordial germ cells (PGCs), the precursors of gametes, are specified from post-implantation epiblast cells in response to bone morphogenetic protein (BMP) signaling at the onset of gastrulation in mouse. Followed by ... -
Characterization of proneural bHLH transcription factor target genes in X. laevis
(2022-09-23)Zc3h12c is a member of the Zc3h12 endoribonuclease family (also known as MCPIP/Regnase), which contains four members (Zc3h12a-c). This family of proteins is characterized by the presence of a single centrally located ... -
Untersuchungen zur Rolle von Mph1 aus Saccharomyces cerevisiae und seines menschlichen Orthologen FANCM bei der Erhaltung der genomischen Integrität
(2022-07-22)Living is life-threatening. Cells can only endure the diverse exogenous and endogenous attacks on their genome because they are equipped with a network of coordinated security measures: the DNA damage response. Repair ... -
On ultrastructure and gene expression during epiblast morphogenesis and axial differentiation in the prestreak embryonic disc of the pig
(2021-09-16)The epiblast of the amniote embryo is of paramount importance during early development as it gives rise to all tissues of the embryonic proper. In most mammals, the epiblast emerges by segregation of the inner cell mass ... -
Mammalian spermiogenesis and the formation of the sperm head to tail coupling apparatus
(2021-08-24)The head-tail coupling apparatus (HTCA), also known as connecting piece, provides the physical linkage between the sperm head and its tail. The HTCA morphogenesis initiates during spermiogenesis and is assembled at the ... -
Development of a biotechnologically enhanced sterile insect technique to fight coleopteran pests
(2021-06-30)Tribolium castaneum commonly referred to as the Red Flour Beetle (RFB) belongs to the class Insecta and order Coleoptera, and it’s the best model organism for coleopterans. About 380,000 coleopteran species, constituting ... -
Identification and Characterization of Novel Genes involved in Quinone Synthesis in the Odoriferous Defensive Stink Glands of the Red Flour Beetle, Tribolium castaneum
(2021-05-26)Defense strategies are common in insects including Coleoptera, the largest animal taxon containing various types of beetles. Stink gland secretion of beetles is playing an important role in their defense against detrimental ... -
Development of Transgenic Sterile Insect Technique Strains for the Invasive Fruit Pest Drosophila suzukii
(2020-12-03)Globalization has contributed enormously to emergence and expansion of invasive pests. A recent example is the invasion in Europe and the USA by the cherry vinegar fly Drosophila suzukii. The pest has high potential to ... -
RNA interference: Process and Application to Pest Control
(2020-07-28)Innovation is one of the keys to ensure effective insect pest control in crop protection. A much discussed novelty to insect pest management is represented by RNA interference (RNAi). Employing this conserved virus defense ... -
Functional analysis of the septate junction protein complex in Drosophila melanogaster
(2019-04-10)Body cavities and external surfaces of metazoic organisms are covered with sheets of epithelial cells that act as physical and chemical barriers. Epithelial tissues divide the body into differentiated compartments with ... -
Development and metamorphosis in the male pedipalp of the cob-web spider Parasteatoda tepidariorum
(2019-02-12)Tracing from marine ancestors, spiders have adapted to a terrestrial lifestyle independent from the insects. Many of the adaptations of spiders to life on land involve the shape and function of their appendages. From these ... -
The early Development of the Germline in Drosophila melanogaster
(2018-12-14)The germline cells are of fundamental importance for all animals as they have the ability to give rise to the next generation. Their precursors, the primordial germ cells (PGCs), are determined very early during animal ... -
Regulatory mechanisms driving motor neuron functional diversification
(2018-06-08)Precise neural control of muscle tone, reflexes, and voluntary movements relies on circuits operating through the fusimotor neurons. Fusimotor neurons or gamma motor neurons (γ-MNs) control motor behavior by tuning the ... -
Exploring morphological innovation and diversification: Analysis of genes involved in gin-trap formation and antenna remodeling during metamorphosis in Tribolium castaneum
(2017-08-18)How morphological traits originate and diversify is a central question in evolutionary biology. Insects are the most diverse group of animals on the planet and over 80% of insect species belong to the subgroup of holometabola. ... -
Comprehensive Morphological and Transcriptomic Analysis of the Chemosensory System in the Red Flour Beetle, Tribolium castaneum
(2016-11-18)The red flour beetle, Tribolium castaneum is an emerging coleopteran model system and thus represents the largest insect order with several agricultural and forest pests. Despite the ecological and economic importance of ... -
Analysis of peroxisomal turnover and myelin maintenance in mice with oligodendrocyte-specific MFP2-deficiency
(2016-11-02)Although caused by distinct genetic mutations, the peroxisomal disorders X-linked adrenoleukodystrophy (X-ALD), pseudoneonatal adrenoleukodystrophy (pseudo NALD), and neonatal adrenoleukodystrophy (NALD) share several ... -
Genetic Evidence For Neuron-Glia Metabolic Coupling In The CNS
(2016-07-27)The active contribution of oligodendrocytes and astrocytes to sustain brain physiology was completely underestimated, but severe consequences of their dysfunction in various diseases and glia-specific mutants emphasized ... -
Oxidative stress pathways in the pathogenesis of renal fibrosis
(2016-05-23)In the pathogenesis of renal fibrosis, oxidative stress (OS) enhances the production of reactive oxygen species (ROS) leading to sustained cell growth, inflammation, excessive tissue remodelling and accumulation, which ... -
Multiplexed cell-based assays to profile GPCR activities and cellular signalling
(2016-03-23)G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors that are implicated in the physiological regulation of many biological processes. They mediate signals through complex networks of G ... -
Proteolytic Processing of Drosophila melanogaster FGFs
(2016-02-11)FGF signalling is of major importance for organisms ranging invertebrates to mammals were it is involved in a broad range of processes throughout the development and adulthood. FGF signalling in Drosophila melanogaster ...