Blättern Fakultät für Chemie (inkl. GAUSS) nach "Ackermann, Lutz Prof. Dr." Betreuer
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Electrochemical C-H Activations with 3d and 4d Transition Metal Catalysts
(2021-12-20)The oxidative metal-catalyzed C–H activation of inert bonds is a powerful tool for the functionalization of complex molecules. This platform allowed the broadening of the organic chemists’ toolbox and improved the ... -
Electrochemical C–H Activation by Ruthenium and Palladium Catalysis
(2024-04-19)The emergence of direct functionalizations of C−H bonds offers efficient alternatives to traditional cross-coupling reactions, thereby saving time and costs. However, oxidative C−H activation often depends on stoichiometric ... -
Entwicklung katalytischer Kreuzkupplungs- und Hydroaminierungsreaktionen
(2008-11-13)In recent years great efforts have been taken for the development of highly active catalysts in the field of hydroamination- and cross-coupling-reactions. However, there is still a lack of ... -
Experimental and Computational Studies on Ruthenium- and Manganese-Catalyzed C-H and C-C Activation
(2019-11-07)During the last years, transition metal-catalyzed C–H and C–C activation has emerged as a powerful tool for the selective construction of C–C and C–Het bonds. In this context, a detailed mechanistic understanding of these ... -
Homogeneous and Heterogeneous Chelation-Assisted Ruthenium(II)-Catalyzed C–H Functionalizations
(2017-01-03)Ruthenium(II)-catalyzed direct C–H functionalizations have emerged as a powerful tool for organic chemists to construct C–C and C–Het bonds. In order to rationally improve the efficiency of these methods a mechanistic ... -
Iron- and Ruthenium-Catalyzed Site-Selective C–C Forming Direct C–H Functionalizations
(2015-04-09)During the last decades, C‒C bond forming reactions have been established as one of the most important tools for modern organic synthesis for the functionalization of otherwise difficult to activate compounds. The inexpensive ... -
Iron-Catalyzed C–H/N–H Activations for Annulation of Allenes, Alkynes, and Bicyclopropylidenes
(2020-11-16)Iron-catalyzed C–H/N–H activations for the annulation of allenes, alkynes, and bicyclopropylidenes were realized by using a customizable clickable triazole amide under mild reaction conditions. The powerful iron catalysis ... -
Kupfer- und palladiumkatalysierte N H- und C H-Bindungsfunktionalisierungen zur effizienten Synthese von Heterocyclen
(2011-05-20)Several approaches for the synthesis of substituted indoles, (benz)oxazoles and oxazolines using copper- and palladium-catalyzed reactions are examined. A copper-catalyzed synthesis of ... -
Late-Stage Peptide Diversification via Transition Metal-Catalyzed C─H Activation
(2020-10-13)The late-stage modification of peptide is of great value to drug discovery and medicinal chemistry. Metal catalyzed C─H activation has emerged as efficient and step-economic strategy for post-translational peptide engineering. ... -
Late-Stage Peptide Functionalization by Ruthenium-Catalyzed C H Arylations and Alkylations
(2018-11-08)The thesis contents methods for the selective activation and functionalization of C–H bonds of the C2 position of a tryptophan moiety incorporated into peptides. Palladium-catalyzed C-H arylation reactions applying ... -
Late-Stage Peptide Functionalization by Transition Metal-free and Palladium-Catalyzed C–H Arylations
(2022-03-31)The focus of this thesis was set on the late-stage modification of peptides through transition metal-free and palladium-catalyzed C–H arylations. At first, the scope of the transition metal-free C2-arylation of the ... -
Merging Electrosynthesis with 3d Transition Metal-Catalyzed C–H Transformations
(2021-07-12)In recent years, oxidative C–H transformations have emerged as increasingly powerful tools in molecular syntheses. However, despite great progress towards more atom and step economic synthetic methods, oxidative couplings ... -
Metallaelectro-Catalyzed C─H Activations by 3d Transition Metals
(2020-09-17)The functionalization of C–H bonds largely relies on organic (pseudo-)halide electrophiles as coupling partners, which results in stoichiometric quantities of undesired by-products. Therefore, to achieve better resource ... -
Nickel-Catalyzed Secondary Alkylations and Fluoroalkylations via C–H Activation
(2016-07-15)In the past several decades, transition metal-catalyzed cross-coupling reactions proved to be of utmost importance within organic synthesis. However, required prefunctionalization of substrates remained as a major disadvantage ... -
Resource-Economical C–H Activation for Late-Stage Functionalization
(2021-07-07)Organic synthesis has traditionally relied on step-, time- and resource-intensive strategies, namely the functional group interconversion and, more recently, on cross-coupling reactions. These approaches have enabled the ... -
Resource-Economical Synthesis by Selective Metal-Catalyzed C–H Activations
(2021-04-30)The advent of new synthetic strategies has enriched the synthetic organic chemistry to access molecules with tremendous complexity. In this context, transition metal-catalyzed C−H activation has emerged as a powerful tool ... -
Ruthenium(II) biscarboxylate-Catalyzed C(sp2)-H and C(sp3)-H Functionalizations by Chelation Assistance
(2016-12-06)Functionalizations of C(sp2)-H and C(sp3)-H bond were achieved by Ruthenium(II) biscarboxylate complexes in an atom- and step-economic fashion. -
Ruthenium(II)- and Copper(I)-Catalyzed C–H Functionalizations
(2015-12-17)Transition metal-catalyzed cross-coupling reaction as one of the greatest chemical innovations of 20th century has to utilize stoichiometric amounts of prefunctionalized reagents. In comparison, the transition metal-catalyzed ... -
Ruthenium(II)-Catalyzed C-H Arylations of Arenes
(2016-10-10)The goal of this work was to devise environmentally friendly and cost-effective novel concepts for the efficient synthesis of biaryl units as core structure in biologically active compounds, which are of great importance ... -
Ruthenium(II)-Catalyzed C-N, C-O and C-C Formations by C-H Activation
(2017-02-16)Ruthenium catalyzed C-N, C-O and C-C formation is achieved by C-H activation. access to primary aminoketones leds to synthetic synthons for different heterocycles. removable and reusability was shown first time in C-O bond ...