Browsing Fakultät für Chemie (inkl. GAUSS) by Referee "Koszinowski, Konrad Prof. Dr."
Now showing items 1-20 of 67
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Reductive Elimination in Transition Metal Complexes: Selectivity and Trends across the d-Block
(2025-08-22)Transition metal-catalyzed cross-coupling chemistry requires more insights into the details of diverse and complex reaction mechanisms of different metals and the factors influencing them. This thesis aimed to investigate ... -
Total Syntheses of natural products derived from the liverwort using pi-acidic catalysts
(2025-07-31)Over the years, many natural products and chemical structures derived from plants, animals, microorganisms and marine organisms have been used as an inspiration for the synthesis of small molecules. The knowledge of using ... -
Computational and Mass-Spectrometric Investigation of the Structure and Reactivity of Coinage-Metal Ate Complexes and Thermometer Ions
(2025-07-28)Over the past decades, the combination of electrospray ionization (ESI), multi-stage mass spectrometry (MS^n) and computational methods has proven to be a powerful tool for fundamental studies on organometallic chemistry. ... -
N-Heterocyclic Electroauxiliaries for the Generation of Alkyl Radicals via C−C Bond Cleavage
(2025-07-17)Alkyl radical precursors are essential for a wide variety of photocatalytic and 3d-metal-catalyzed C–C bond forming reactions. In the last decade, neutral organic heterocycles as electroauxiliaries have become reliable ... -
Investigation of Nuclear Hyperfine Coupling in H2 Heterodimers Using Rotational Spectroscopy
(2025-05-20)Rotational spectroscopy of gas phase compounds is a powerful technique for structure determination through the unique moments of inertia of a molecular system. It is sensitive angular momentum coupling; therefore, complicated ... -
Enantioselective Electrochemical C–H Activation with Cobalt, Nickel, and Iron
(2025-04-04)The enantioselective functionalization of otherwise inert C–H bonds to assemble chiral molecules has become an increasingly powerful tool in molecular synthesis. In spite of significant advances in this domain, the ... -
Investigation of Framework-forming Aggregation of Peptide Helices on Membrane Surfaces
(2025-02-14)This study presents the development and investigation of peptide-based systems designed to induce controlled aggregation on membrane surfaces, potentially facilitating cell signaling by promoting lipid raft formation. The ... -
Identification and Characterization of Intermediates in Transmetalation Reactions from Boron to Lithium and Copper
(2025-02-14)Transmetalation is a crucial elementary step in cross-coupling reactions. In this context, boron nucleophiles are especially popular and versatile, however, the fundamental details of transmetalation reactions involving ... -
Enantioselective Synthesis and Postsynthetic Functionalization of Thiahelicenes and their Oxa-analogues
(2025-01-30)Based on the Alcarazo group’s experience in enantioselective Au(I)-catalyzed synthesis of (hetero)helicenes employing alkyne hydroaryration reactions, the gold precatalyst 188c, combining a chiral BINOL-derived backbone ... -
Manganese and Ruthenium Catalysis for Sustainable C–H Functionalizations and Polymer Synthesis
(2024-10-28)The ever-growing scarcity of resources, energy crises, and environmental pollution demand the development of sustainable chemical processes for C–C bond formations and efficient post-consumer plastic waste recycling. While ... -
Metallaelectro-Catalysis and Aryl Sulfonium Salts in Sustainable C–H Activations and Late-Stage Diversification
(2024-09-17)In the past decades, organic chemistry was dominated by functional group interconversions and cross-coupling chemistry. These techniques allowed the synthesis of a plethora of highly complex molecules and are established ... -
Enabling Novel Fluoroalkylation via Sulfonium Salt Transfer Reagents
(2024-08-26)Over the past four decades, sulfonium salt-based transfer reagents have evolved into widely recognized tools for fluoroalkylation in the synthetic chemistry community. These reagents have enabled the incorporation of various ... -
Synthesis of Novel Sulfur(VI) Reagents and the Regioselective Functionalization of Helicenes by Hypervalent Reagents
(2024-06-28)The synthesis of novel sulfur(VI) reagents was investigated. For this purpose different sulfurane oxides were synthesized. The functionalization of these compounds was unsuccessful due to decomposition or inertness of the ... -
meta-C−H Functionalization and Sustainable Electro- /Photoelectrocatalytic C−H/Si−H/Ge−H Activation
(2024-06-18)C−H activation provides a crucial new tool for the construction of C−C bonds in organic chemical synthesis, especially for agrochemistry, the pharmaceutical industry, and materials science, using a large number of existing ... -
Palladium- and Ruthenium-Catalyzed C(sp2)–H and C(sp3)–H Arylations
(2024-06-05)Catalysis is arguably the most impactful area of chemistry for society today, driven by the urgent need for highly efficient and environmentally benign reactions. C−H activation, which allows for the direct introduction ... -
Electrochemical C–H Activation by Ruthenium and Palladium Catalysis
(2024-04-19)The emergence of direct functionalizations of C−H bonds offers efficient alternatives to traditional cross-coupling reactions, thereby saving time and costs. However, oxidative C−H activation often depends on stoichiometric ... -
Sustainable Ruthenium- and Rhodium-Catalyzed C−H Activations with Photochemistry and Electrochemistry
(2024-03-18)Cross-coupling chemistry stands out as a fundamental tool in synthetic organic chemistry for forging C‒C and C‒Het bonds. However, the necessity for substrate prefunctionalization imposes significant sustainability challenges ... -
Weiterentwicklung diffusionsspektroskopischer NMR-Methoden für metallorganische Schlüsselverbindungen
(2023-10-02)This work has extended the development and application of NMR diffusion spectroscopic techniques for the determination of the molecular weight of compounds in solution. In the process, methylcyclohexane-d14 was added to ... -
Barriers of Protonation Reactions of Organometallics
(2023-09-20)Protonation reactions are entirely understood for simple organic and inorganic molecules and there are elaborated concepts to describe such acid-base reactions in both the solution and gas phase. For organometallic species, ... -
Diversity-Oriented Assembly of C-Glycosides via Late-Stage C−H Glycosylation
(2023-08-29)C-glycosides are widely distributed structural motifs found in natural products and commercially available drug molecules. Due to the stability of glycosidic C-C bonds against chemical and enzymatic hydrolysis, only ...