Blättern Naturwissenschaften, Mathematik und Informatik nach Betreuer & Gutachter "Wahl, Markus Prof. Dr."
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Investigations into the regulation of histone H2B monoubiquitination
(2011-10-26)Transcription-associated chromatin modifications are recognized now as important regulators of gene expression. One of them, the monoubiquitination of lysine 120 of histone H2B (H2Bub1), ... -
Structural and functional characterization of the autophagy proteins Atg5 and Atg16L1 and their interaction partners
(2011-05-26)Autophagy is a degradative pathway conserved in eukaryotes. During autophagy a portion of the cytoplasm is sequestered by a de novo forming isolation membrane resulting in the formation of ... -
Purification and crystallization of spliceosomal snRNPs
(2009-02-26)In eukaryotes, the non-coding sequences (introns) of precursor messenger RNA are excised by a large ribonucleoprotein complex, the spliceosome. The core components of the spliceosome are ... -
Functional and structural investigation of spliceosomal snRNPs
(2009-01-20)The expression of most eukaryotic protein-encoding genes involves precursor messenger RNA (pre-mRNA) processing steps including pre-mRNA splicing. Pre-mRNA splicing is catalyzed by a ...