Dokumente Fakultät für Chemie (inkl. GAUSS) nach Titel
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Darstellung bor- und phosphorhaltiger Ringe durch Reaktionen von Halogenboranen und -phosphanen mit Bis(tert.-butyl-methyl)ketazin
(2004-10-22)The first part of this thesis refers to the reactions of boroles, especially substitutions of remaining halogens and dehydrohalogenation reactions. The second part deals with similarities ... -
Darstellung neuer Organometallhalogenide mit Elementen der 13. und 14. Gruppe des Periodensystems und Versuche zur Synthese von Organogermanolen
(2003-08-18)The first part of the thesis is focused on the synthesis and structural characterisation of organometal halides of group 13 of the periodic system. Fluorination of [MeAlN(2,6-i-Pr2C6H3)]3 ... -
Data Quality Bench-Marking for High Resolution Bragg Data
(2015-03-05)The thesis deals with data quality bench-marking for high resolution Bragg data. It compares and evaluates Bragg data from various radiation sources and different detection types. Two different small molecules containing ... -
Dehydrorabelomycin-1-O-α-L-rhamnopyranoside, Actinofuranone C and Further New Bioactive Secondary Metabolites from Terrestrial Streptomyces spp.
(2011-09-22)Natural products have been used to combat infectious diseases since ages. However, increased resistance to existing antibiotics and emergence of new diseases stimulated the development of ... -
Design and Characterisation of Multifunctional Tools for the Elucidation of the Cu+ Chemistry in Alzheimer`s Disease
(2013-09-06)Alzheimer’s disease is the most common neurodegenerative disease in the world. Alzheimer’s disease is clinically characterised by decreased cognitive performance and pathologically characterised by formation of fibrillar ... -
Design and synthesis of multifunctional ligands to study and prevent aggregation processes in Amyotrophic Lateral Sclerosis proteins
(2021-02-22)Amyotrophic lateral sclerosis (ALS) is an incurable lethal disease that affects motor neurons and its heterogeneity is reflected in various mutations among the sporadic ALS (sALS) and familial ALS (fALS) disease types. ... -
Design and synthesis of small organic molecules to stabilize ALS-associated SOD1 mutants
(2021-06-25)Amyotrophic Lateral Sclerosis is a globally occurring neurodegenerative disease with serious implications for the patient’s life as well as imposing a heavy economic burden both on the affected individuals and society. Due ... -
Design of Phosphorus Centered Janus Head Ligands
(2012-02-03)The scope of this thesis was the preparation of a Janus Head ligand based on the N,P,N ligand di-2-picolylphenylphosphane and the synthesis of different metal complexes containing this Janus ... -
Design und Synthese neuer flüssigkristalliner Substanzen mit zentraler Bicyclo[3.1.0]hexaneinheit
(2003-07-10)Starting from the first observations of the phenomenon of liquid crystallinity by Reinitzer in 1888 and by Lehmann in 1889, the design and preparation of molecules possessing liquid crystalline ... -
Design, Synthesis and Applications of new cationic ligands of the 15th main group elements
(2017-12-08)The dissertation focuses on the development of new cationic phosphines and their applications in transition metal catalyses. In pi-acid catalysis they proved their superiority in comparison with state of the art ligand ... -
Designing New Heterometallic [2 x 2] Grids using Pyrazolate-bridged Ligands
(2020-02-18)This dissertation focusses on designing new heterometallic [2 x 2] grids based on pyrazolate-bridged ligands exhibiting interesting magnetic and redox properties. To date, numerous homometallic metallogrids have been ... -
Designstrategien für photoschaltbare Polymer-Nanokomposite
(2016-11-17)Silica and gold nanoparticles were functionalized with a developed photo responsive polymer in order to construct tailored self-assembled architectures from polymer nanocopmosites. Silica surfaces were functionalized with ... -
Detailed Investigations into the Propagation and Termination Kinetics of Bulk Homo- and Copolymerization of (Meth)Acrylates
(2005-08-16)Three aspects of free-radical polymerization have been addressed: (i) the propagation rate in acrylate/methacrylate copolymerizations, (ii) the chain-length dependence of the termination ... -
Detecting the Undetectable: Functional Protein Motions in the Hidden Timescale Window Revealed by NMR Relaxation Measurements
(2022-05-19)About 50 years ago, even before NMR was ready to determine structure of proteins, it could unveil a surprising motion in aromatic side-chain (Wuthrich & Wagner, 1975) from 1D 1H spectra. With decades of development, NMR ... -
Detection of Monoamine Mediated Immune Cell Communication by Nanosensors
(2022-11-11)The immune system comprises many organs, organ systems, cell types and secretory components that together form an intricate host defense network encompassing physical, biological and chemical barriers. Secretory components ... -
Determinants of water and ion permeation through nanopores studied by Molecular Dynamics simulations
(2008-05-27)Membrane channels facilitate the transport of matter through the cell membrane, and therefore play a crucial role in life. The knowledge of the structure-permeability relationships in model channels is essential for the ... -
Development and application of NMR methods for challenges in drug discovery
(2013-05-03)NMR spectroscopy plays an important role in all stages of the drug discovery process. Namely in the structure elucidation of natural products, synthetic ligands and metabolites, as well as a high-throughput screening ... -
Development and Application of NMR-methods for Structural Investigations of Small Molecules and Proteins
(2007-05-29)The elucidation of the relative stereochemistry of asymmetric centers of organic molecules is an important challenge in chemistry since it requires the simultaneous determination of ... -
Development of a Biomembrane Sensor Based on Reflectometry
(2013-09-13)Membrane proteins play central roles in many significant cellular processes such as signal transduction, cell adhesion and immune recognition reactions. As a result, they gained substantial pharmacological significance, ...