Dokumente Fakultät für Chemie (inkl. GAUSS) nach Titel
Anzeige 227-246 von 702
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Herstellung und Charakterisierung von Polymernetzwerken im Kontext der präparativen Membranchromatographie
(2022-03-04)Preparative chromatography is an essential part in the industrial purification of biopharmaceuticals and thus allows the targeted therapy of severe diseases like cancer, multiple sclerosis or rheumatism. It enables the ... -
Heterogenität als Herausforderung und Chance in der Hochschulausbildung in Zeiten der digitalen Transformation
(2021-11-22)Industry 4.0, Working World 4.0 and Chemistry 4.0 - Today's society is in a constant state of change due to digitalization. Therefore, lifelong learning is essential in order to meet the challenges within society and the ... -
High-field EPR and ENDOR spectroscopy for proton-coupled electron transfer investigations in E.coli ribonucleotide reductase
(2012-02-27)Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides in all organisms, thereby providing the essential precursors for DNA synthesis and replication. ... -
High-Precision Particle Arrangement in Gold‒Polymer-Nanocomposites using RAFT Polymerization
(2016-11-17)This thesis provides a comprehensive analysis of the scientific background on nanocomposites generated via reversible-deactivation radical polymerization (RDRP) techniques. Starting from this basis, nanocomposites with the ... -
Hitzeinduzierte Radikalbildung während der thermischen Holzmodifizierung
(2020-03-10)In this thesis the hardwood and the softwood were thermally modified to investigate the effect of heat on the chemical structure of the wood and the heat induced radical formation during wood modification. Different ... -
HIV-1 Nef destabilisiert artifizielle Membransysteme: Untersuchung der Bedeutung des Myristoylankers und des positiven Ladungsclusters
(2009-06-22)The HIV-1 Nef protein belongs to the so-called accessory proteins and is critical for optimal viral replication and the pathogenesis of AIDS. It is supposed that the functions of Nef require ... -
Hoch cytotoxisches Kettapetin, Bhimamycine mit ungewöhnlichen Chromophoren und weitere neue Sekundärstoffe aus terrestrischen und marinen Bakterien
(2006-02-27)Nature is a source of medicinal agents since thousands of years, and an impressive number of modern drugs has been isolated from natural habitats, many based on their use firstly in traditional ... -
Hochohmige porenüberspannende Lipidmembranen: Elektrochemische Untersuchungen zur Aktivität von Gramicidin und Bacteriorhodpsin
(2009-07-14)To study transmembrane proteins they need to be integrated in a lipid environment to preserve their functionality. For this purpose, model membranes have been developed which allow the ... -
Homo- and Mixed-valence [2 × 2] Grid Complexes
(2016-04-21)In this work homo- and mixed-valence [2 × 2] grid-like complexes were studied in detail. Here, the multifunctionality features of these iron and cobalt grids are clearly illustrated in properties: 1) the electrochemistry ... -
Homogeneous and Heterogeneous Chelation-Assisted Ruthenium(II)-Catalyzed C–H Functionalizations
(2017-01-03)Ruthenium(II)-catalyzed direct C–H functionalizations have emerged as a powerful tool for organic chemists to construct C–C and C–Het bonds. In order to rationally improve the efficiency of these methods a mechanistic ... -
Host-Guest Chemistry of Acridone-based Coordiantion Cages
(2018-06-07)Supramolecular coordination cages, assembled from organic ligands and metal cations, are of broad interest due to their versatile topologies and properties. Discrete cages often possess a secluded cavity, which allows ... -
Hybrid Simulation Methods for Systems in Condensed Phase
(2018-05-23)Reactions in solution are important in the chemical and pharmaceutical industry as well as in biochemical contexts. In fact, the solvent effects are stronger than many other factors and can slow down or speed up a reaction ... -
Hybrids of SNARE Transmembrane Domains and Artificial Recognition Motifs as Membrane Fusion Inducing Model Peptides
(2018-03-13)Protein mediated fusion of membranes is a crucial biological process. For instance, SNARE (soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein receptor) proteins are involved in neuronal exocytosis. However, ... -
Hydrogen Bonds and Electrostatic Environment of Radical Intermediates in Ribonucleotide Reductase Ia
(2016-06-16)Ribonucleotide reductase connects the RNA and the DNA world via strictly controlled radical chemistry that reduces all four essential ribonucleotides to deoxyribonucleotides. In RNR Ia, the starting point is the µ-oxo ... -
Hyperpolarisierte Kontrastmittel in der Magnetresonanz
(2022-02-24)Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are powerful techniques with applications ranging from chemical analysis to medical diagnostics. However, they are limited by their low sensitivity which ... -
Implementing Ion Imaging to Probe Chemical Kinetics and Dynamics at Surfaces
(2018-07-03)In this thesis I present a novel surface science apparatus and new methods to measure and analyze reaction kinetics at surfaces. By combining crossed-beam surface scattering with universal fs-laser ionization and ion ... -
In and through the membrane by solid-state NMR: investigations of the human voltage-dependent anion channel 1 and Nup98-derived FG-domains
(2022-02-22)Magic-angle-spinning NMR spectroscopy is a powerful tool for the investigation of protein structure, dynamics and interactions at atomic resolution. We have applied this technique to investigate two widely different systems: ... -
In vitro studies of protein interactions on substrate supported artificial membranes
(2013-02-12)Protein interactions that take place at the interface of a membrane are abundant within cellular organisms. Hence, surface coupled protein interactions are a matter of ongoing scientific investigation. In this work, elected ... -
Indole Alkaloids as Potential Leads in Drug Discovery and Further Secondary Metabolites from Terrestrial and Marine Bacteria
(2012-01-04)Microorganisms take a large influence on ecological and symbiotic interactions in long-term relationships that are moderated by secondary metabolites with often-unique structure and biological ... -
Inelastic H-Atom scattering from ultra-thin films
(2018-09-05)This thesis contains experimental and theoretical fundamental studies of energy transfer processes on various surfaces via inelastic hydrogen atom scattering using the Rydberg atom tagging machine. The initial investigations ...