Browsing Molekulare Medizin by Advisor "Reichardt, Holger Prof. Dr."
Now showing items 1-5 of 5
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Novel therapeutic approaches to treat inflammatory conditions with glucocorticoid and calciferol nanoparticles in vivo and in vitro
(2023-01-10)The body is constantly confronted with environmental threats and sometimes the entry of pathogens leads to severe inflammatory conditions such as sepsis or acute lung injury (ALI). Both diseases are characterized by a ... -
Mechanisms of Glucocorticoids in the modulation of Graft-versus-Host Disease and the Graft-versus-Leukemia Reaction
(2020-07-31)Acute graft-versus-host disease (aGvHD) is a severe complication that frequently occurs after allogeneic hematopoietic stem cell transplantation and results in a high transplant-related morbidity and mortality. Glucocorticoids ... -
Airway Epithelial Cells as Targets of Glucocorticoid Therapy in Inflammatory Lung Diseases
(2017-02-24)Glucocorticoids (GCs) have been a mainstay in the treatment of various autoimmune and allergic diseases for many decades due to their potent anti-inflammatory activities. The beneficial effects of GCs are mediated by the ... -
Myeloid corticoid receptors in CNS autoimmunity: Old targets for novel therapies
(2016-10-21)Since the 1950s, glucocorticoids (GCs) have been the most widely employed drugs in the treatment of inflammatory and autoimmune disorders, such as multiple sclerosis (MS). Short-time application of high-dose GCs is the ... -
Ex vivo und in vivo Modulation von Makrophagen und T-Zellen als therapeutisches Prinzip der aGvHD
(2015-10-15)Acute Graft-versus-Host disease (aGvHD) is a severe complication of hematopoietic stem cell transplantation. Glucocorticoids (GCs) are a mainstay of aGvHD therapy due to their potent anti-inflammatory and immunosuppressive ...