Browsing Molekulare Medizin by Referee "Papantonis, Argyris Prof. Dr."
Now showing items 1-4 of 4
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GSK3β-mediated DNA damage repair in pancreatic cancer
(2021-11-24)In this study we aimed to determine a deeper mechanistic understanding of GSK3β and its influence on pancreatic cancer behavior. Specifically, we examined the effect of GSK3β on transcriptional regulation and function ... -
Interplay of ARID1A and EGFR signaling in controlling acinar cell reprogramming in the pancreas
(2021-03-18)Based on a high degree of cellular plasticity and triggered by external (e.g. inflammation) or internal (e.g. oncogenic pressure) signals, pancreatic acinar cells can undergo reprogramming processes resulting in acinar-to-ductal ... -
MCL-1, BCL-xL and Casp-3 as key regulators in thymus homeostasis and thymic epithelial tumors
(2021-12-23)As a primary lymphatic organ, the thymus is responsible for T cell development and the establishment of the adaptive immune system. The homeostasis and proper function of the thymus epithelium require the strict regulation ... -
Molecular mechanisms of TBX5-related conduction disorders
(2021-08-24)Background Cardiovascular disease is a common cause of death. About 60 % of cardiovascular mortality is attributable to sudden cardiac death, mostly caused by arrhythmia. The origin of arrhythmia can be an underlying ...