Comparative studies on regulation of SNARE complex formation by the SM protein Sly1p

Vergleichende Studien zur Regulation der SNARE Komplex Bildung durch das SM protein Sly1p

von Fatma Esra Demircioglu
Dissertation
Datum der mündl. Prüfung:2011-11-01
Erschienen:2012-06-11
Betreuer:Prof. Dr. Dirk Fasshauer
Gutachter:Prof. Dr. Dirk Fasshauer
Gutachter:Prof. Dr. Markus Wahl
Gutachter:Prof. Dr. Stefan Eimer
Zum Verlinken/Zitieren: http://dx.doi.org/10.53846/goediss-3262

 

 

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Zusammenfassung

Englisch

Sec1/ Munc18 (SM) proteins are indispensible regulators of intracellular membrane fusion. In general, the high-affinity binding partners of SM proteins are Qa-SNAREs (syntaxins). Despite the high structural homology among SM proteins, different modes are proposed for their association with syntaxins. Neuronal Munc18a binds to a ‟closed conformation
Keywords: Membrane fusion; Sly1p; SNARE; syntaxin; Sed5p; ER; Golgi
Schlagwörter: Membranfusion; Sly1p; SNARE; Syntaxin; Sed5p; ER; Golgi
 
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