Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Köster, Sarah Prof. Dr."

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    • Single-molecule measurements of Kinesin motor proteins 

      Düselder, André (2014-03-13)
      This thesis covers the developments and new findings on different regulatory processes in Kinesin-5 motor proteins. The first two chapters give a general introduction into motor proteins and some of the well established ...

    • STED Microscopy of FRET Pairs 

      Loidolt-Krüger, Maria (2018-05-18)
      Förster resonance energy transfer (FRET) is a popular tool in life sciences, for example to detect protein-protein interactions and ligand binding, or to construct fluorescent biosensors for metabolites or ions. Obtaining ...

    • STED Microscopy with Scanning Fields Below the Diffraction Limit 

      Göttfert, Fabian (2016-11-17)
      Since its development, STED microscopy has been used extensively for imaging biological samples. To label structures of interest, fluorescent proteins and organic dyes are used almost exclusively. However, these labels ...

    • Stress-Strain Behavior of Single Vimentin Intermediate Filaments 

      Block, Johanna Lena (2018-08-09)
      Cells are the basic unit of living organisms and consist of a cytoplasm, which is enclosed by a membrane. As building blocks of life with a plethora of functions, cells have to be equipped with a high degree of mechanical ...

    • Structure and dynamics of stress fibers in adult stem cells 

      Wollnik, Carina (2016-07-19)
      Since decades, the differentiation potential of adult human mesenchymal stem cells (hMSCs) is investigated. They feature the ability for differentiation into various cell types, like cartilage, fat, nerve, muscle and ...

    • The Influence of Substrate Elasticity and Shear Rate on Human Blood Platelet Contraction 

      Hanke, Jana (2018-09-12)
      Human blood platelets are small, anucleate cell fragments that are important for the life-saving process of haemostasis, i.e. the process of wound healing. Upon injury, blood platelets adhere to the exposed extra-cellular ...

    • Tracking Assembly Kinetics of Intermediate Filaments 

      Saldanha, Oliva (2017-04-13)
      Vimentin is an intermediate filament (IF) protein in eukaryotic cells and together with other IFs, actin filament and microtubules plays an instrumental role in providing stability and mechanical properties to the cell. ...