Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Fiala, André Prof. Dr."
Anzeige 1-20 von 27
-
A Functional Characterisation of Drosophila Chordotonal Organs
(2013-06-27)Functional properties of the Drosophila FCO (femoral chordotonal organ) can be dissected by use of the Gal4-UAS system in combination with transcuticular in vivo Calcium imaging. As sinusoidal stimulation at relative ... -
A novel membrane-binding probe for the morphological and molecular characterization of synaptic vesicle recycling pathways
(2015-05-12)An important anatomical feature of neuronal synapses is the presynaptic bouton, a structure that isolates synaptic vesicle recycling from constitutive membrane trafficking pathways. However, in some neurotransmitter-releasing ... -
Aberration correction in STED microscopy
(2019-11-21)In the last decade, superresolution microscopy techniques became a valuable tool to study sub-cellular structures with a resolution below the diffraction limit. The use of superresolution for brain research requires to ... -
Acetyltransferase TIP60/KAT5 regulates the Drosophila Circadian Clock
(2016-10-14)Endogenous clocks control behavioral and physiological processes in a rhythmic fashion exhibiting periodicity of ~24 h. Drosophila exhibits a robust rhythm in activity/rest patterns which is controlled by circadian pacemaker ... -
Analyzing receptor responses in the Drosophila Johnston's organ with two-photon microscopy
(2017-07-31)Hearing organs rely on force-gated ion channels to convert the mechanical energy imposed by sound into receptor potentials usable by the nervous system. So far, little is known about the identity and working mechanisms of ... -
Arrhythmia termination using Global Optogenetic Stimulation in ChR2 mice hearts
(2021-03-04)Cardiac arrhythmias represent a health threat worldwide that can end in sudden death. Treatments which include electrical shocks, anti-arrhythmic drugs and ablation show various disadvantages such as discomfort for the ... -
Axonemal dyneins and force generation by neurons in Drosophila melanogaster ear
(2014-05-26)Analogous to vertebrate hair cells, the mechanosensory cilia of Drosophila auditory neurons are motile and serve dual, transducing and actuating roles. Structurally, the latter cilia resemble non-motile primary cilia, ... -
Biophysical modeling of information processing in the <i>Drosophila</i> olfactory system
(2014-04-24)Fruit flies (Drosophila melanogaster) rely on their olfactory system to process environmental information. Although extensive studies have helped neurobiologists to understand the basic molecular and cellular mechanisms ... -
Computational modeling of neuronal circuits: heterogeneous connectivity and nonlinear transformation in olfactory processing
(2015-05-05)The first processing circuit in the olfactory system (antennal lobe or olfactory bulb) exhibits several astonishing nonlinear features, but how these characteristics emerge collectively in olfaction remains an open question. ... -
Context, circuit and modulation of courtship signal selection in Drosophila
(2023-03-23)Communication is multi-modal -- when we interact, we speak, gesticulate, and touch. However, the neural computations and circuits that select and coordinate these communication signals are unclear. We address this issue ... -
Developmental Studies on Eye Types and Pedipalps in Parasteatoda tepidariorum
(2017-12-21)Arthropods are by far the most species rich phylum in the animal kingdom and their evolutionary success is at least in part rooted in their diverse morphology. Despite these morphological differences, arthropods share a ... -
Evolution of central complex development: Cellular and genetic mechanisms
(2019-11-11)Brains are conserved between insect species, as they consist of a set of anatomically similar areas, or neuropils. Simultaneously, these neuropils differ in size, shape, position and developmental timing between insect ... -
Genetics of Drosophila hearing
(2013-10-04)By probing Johnston’s organ function in mutant fly strains, mutations in forty-four genes that affect Drosophila hearing have been identified. This result increases the list of genes that are known for audition by 180 % ... -
Linking senses: the genetics of Drosophila larval chordotonal organs
(2018-08-06)Sensory systems have evolved in all organisms to detect changes in the environment or their internal state. Even though they are essential for fitness and survival, their phylogenisis is still unclear. The protosensory ... -
Network formation and reorganization of the olfactory system of Xenopus laevis
(2022-03-03)The olfactory system is a window to the chemical world, that permits each species to adapt to novel spaces and situations. Despite the various phylogenetic adaptations, this sensory system maintains similar functional and ... -
Neural circuit plasticity underlying learning and memory in Drosophila melanogaster: from synaptic connections to behavior
(2023-05-12)Understanding the principles behind olfactory higher-order associative chains formation in Drosophila is one step further into unraveling the essence of learning and memory. However, the rationale behind such mechanisms ... -
Neural Principles Underlying Learning and Memory in Drosophila melanogaster
(2021-03-19)The relay of information from external sensory organs to brain centres that ultimately control behavioural output dictates how an animal interacts with its environment. This process is integral to survival, allowing for ... -
Neuronal Circuit Dissection in the Drosophila Brain: the Role of Serotonin-Releasing Neurons in Arousal
(2014-08-18)For animals, an optimal arousal state is essential for motivating or inhibiting a specific behavior. Arousal is regarded to be an internal factor that influences the initiation and execution of different behaviors, and is ... -
Nonlinearities in bipolar cells and their role for encoding visual signals
(2019-05-02)Vision begins in the retina, where ganglion cells separate the visual input into ~30 parallel output channels with different response characteristics to visual stimuli. How retinal ganglion cells obtain such a diversity ... -
Olfactory Perception and Physiology in Drosophila melanogaster
(2013-05-22)All animals are able to evaluate an odor by its consequences depending on prior experiences. This includes the possibility to show a resembling response to similar odors with the same consequence as well as a distinct ...