Dokumente GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften nach Gutachter "Gail, Alexander Prof. Dr."
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Neural correlates of action effects anticipation – towards ecological more relevant paradigms
(2023-12-07)Imagine it is Saturday morning and you are going for groceries with your car. Once you arrive at the supermarket, you attempt to reverse park your car in a narrow parking space. You have learned in school, if you want ... -
Force information integration in the primate fronto-parietal reach network
(2023-11-10)The primate sensorimotor system relies on force predictions, when executing a motor command with a certain force. Yet it remains unclear if the sensorimotor system uses these force predictions to prepare a motor command ... -
Simulation of fronto-parietal neural population activity to probe dimensionality reduction methods.
(2022-09-20)Recent developments of optical and electrophysiological recording tools allow the detailed capture of large neuronal populations. Findings show that their activity is constrained to a low-dimensional manifold within the ... -
How nonlinear processing shapes natural stimulus encoding in the retina
(2022-05-31)Understanding natural vision is one of the fundamental goals of sensory neuroscience. The only part of the visual system that may currently be amenable to such a complete understanding is the vertebrate retina, where there ... -
Imaging Network Alterations in Patients With Genetic Generalized Epilepsy and Their Healthy Siblings Using Magneto- and Electroencephalography
(2022-04-05)Genetic generalized epilepsy (GGE) is a common epilepsy syndrome and represents the largest group of epilepsies suspected to have a complex genetic etiology. Specific time windows for age of onset and various seizure types ... -
The impact of reward value on early sensory processing and its interaction with selective attention
(2021-11-22)Reward value affects the earliest stages of sensory perception. Whereas a host of previous studies have investigated the underlying mechanisms of reward-driven modulation of visual perception, reward effects in other sensory ... -
Neuron-level dynamics of oscillatory network structure and markerless tracking of kinematics during grasping
(2021-11-18)Oscillatory synchrony is proposed to play an important role in flexible sensory-motor transformations. Thereby, it is assumed that changes in the oscillatory network structure at the level of single neurons lead to flexible ... -
Auditory associative learning and its neural correlates in the auditory midbrain
(2021-01-08)Interpreting the meaning of environmental stimuli to generate optimal behavioral responses is essential for survival. Simply sensing a sound, without accessing prior knowledge in the brain, will not benefit behavior. How ... -
Neural population dynamics and frontal-parietal circuit for context-dependent sensorimotor computations
(2020-05-27)This dissertation investigated the computational strategies in the primate's brain for goal-directed movement control and the information stream in inter-areal brain circuits. The animal model used in this research was ... -
Information Processing Analysis in Neural Networks
(2019-06-06)Populations of cortical neurons in the fluctuation-driven regime exhibit an ultrafast population response. Some theoretical studies suggest that passive, morphological features of the axon and dendrites determine the ... -
Eye, hand and space representations and causal interference in bihemispheric pulvinar-parietal circuitry
(2019-05-29)Recent research proposes that a proper action is the outcome of continuous competition between multiple frontoparietal neuronal representations of possible response options and this competition is biased by the input ... -
Representation of individual finger movements in macaque areas AIP, F5 and M1
(2019-05-21)The goal of this study was to investigate how individuated finger movements are coded in area AIP, F5 and M1. At the single neuron level, most of the units in all three areas were “broadly tuned”, responding during multiple ... -
Central sound encoding in the inferior colliculus of mouse models for human auditory synaptopathy and neuropathy
(2018-12-20)Auditory neuropathy and auditory synaptopathy are hearing disorders with normal outer hair cell function and cochlear amplification, but an impairment in the function of inner hair cells, their ribbon synapses, or in the ... -
The Principles of Self-Organization of Memories in Neural Networks for Generating and Performing Cognitive Strategies
(2018-12-12)Higher-order animals exhibit the remarkable ability to dynamically adapt to a changing environment. On the neuronal level, they have to form mental representations of specific stimuli, so-called memories. Furthermore, ... -
The role of thalamic pulvinar in eye-hand coordination for goal-directed actions
(2017-12-07)The pulvinar, the largest thalamic complex in primates has largely expanded during primate evolution, along with association cortices. Its dorsal part is anatomically connected to the fronto-parietal network, involved in ... -
The role of attention and adaptation in shaping cortical representations and the perception of abrupt changes in the visual environment
(2017-11-22)The visual system receives a wealth of visual information about objects with changing features in time. Attention is a mechanism allowing us to prioritize the processing of relevant information at the expense of other ... -
Methodological and Cognitice Aspects of transcranial Electrical Stimulation
(2017-04-06)Transcranial electrical stimulation (tES) techniques are based on the external application of low-intensity electrical current to the brain. The external current can modulate cortical excitability by depolarizing or ... -
Towards population coding principles in the primate premotor and parietal grasping network
(2017-01-03)As humans, the only way for us to interact with the world around us is by utilizing our highly trained motor system. Therefore, understanding how the brain generates movement is essential to understanding all aspects of ... -
Neural coding of grasp force planning and control in macaque areas AIP, F5, and M1
(2016-10-27)Much research has been done in the last decades to decipher how the brain controls grasping movements. The anterior intraparietal area (AIP), the hand area of the ventral premotor cortex (F5), and the hand area of the ... -
Neural basis of rule-based decisions with graded choice biases
(2016-07-22)In every hour of every day we are faced with options; which route to take to work, where to go for a meal, which stocks to invest in. However, with limitations of movement, time and budget, our options are constrained. We ...