Browsing GGNB - Göttinger Graduiertenzentrum für Neurowissenschaften, Biophysik und molekulare Biowissenschaften by Referee "Wolf, Fred Prof. Dr."
Now showing items 1-20 of 41
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Feature Selectivity in Synthetic Neuronal Networks
(2024-06-06)A fundamental property of neurons in the primary visual cortex is their preference for orientation of edges. In primates and carnivores orientation selective neurons are organized into functional domains that are arranged ... -
Information, Logic, and Inference in the Analysis of Complex Networks
(2023-12-22)This thesis deals with a range of current topics in information theory and statistics. It consists of five distinct contributions: Chapter 2 focuses on the statistics of single-regression Granger causality estimators. ... -
A theory of inference and learning in cortex with spiking neurons and dendritic error computation
(2023-11-03)How the cortex performs its intricate computations, and how it adapts to the world around it, is one of the central mysteries in neuroscience. It is a longstanding belief that one of the main aims of the brain, and especially ... -
Intercellular Coordination in Epithelial Morphogenesis
(2022-07-26)During the development of an embryo, tissue rearrangements are driven by the precisely coordinated activity of thousands of cells. How this high degree of organization is achieved and regulated is one of the most important ... -
Drift and stabilization of cortical response selectivity
(2021-08-02)Synaptic turnover and long term functional stability are two seemingly contradicting features of neuronal networks, which show varying expressions across different brain regions. Recent studies have shown, how both of these ... -
Super-resolution of PSD95 remodelling during synaptic plasticity
(2021-07-01)Strengthening and weakening of synapses are a fundamental information processing unit within the neuronal circuit of the brain. It has been shown that the most abundant scaffold protein of the postsynaptic density (PSD), ... -
Receptive field organization of motion computation in the fly: a study of cell types and their variability
(2020-12-02)It is believed that knowing all cell types making up a brain will lead to its understanding. Consequently, current efforts focus on classifying cell types according to their anatomical, genetic and physiological properties. ... -
Reverse-time inference of biological dynamics
(2020-10-27)In this work I derive a mathematical theory that allows to infer directional biological dynamics in reverse time starting from their target state. I use this approach to infer an effective model of cell junction shrinkage ... -
Role of mechanosensitive ion channels in coordinated epithelial cell dynamics in Drosophila
(2019-11-20)Epithelial cells are able to sense and mechanically respond to the forces and movements generated and transmitted through their neighbors. These forces are multicellular at the tissue level, and are transmitted via multimeric ... -
Perturbation Growth and Prediction of Extreme Events
(2018-11-15)Extreme events occur in a variety of dynamical systems. Here we employ quantifiers of chaos to identify changes in the dynamical structure of complex systems preceding an extreme event. -
Decoding Cortical Motor Goal Representations in a 3D Real-World Environment
(2018-10-10)In sensorimotor neuroscience a certain motor behavior, and its underlying neuronal mechanism, is usually studied in isolation and tightly constrained by the experimental setting to provide interpretable results. When ... -
Chaotic Neural Circuit Dynamics
(2018-02-09)Information is processed in the brain by the coordinated activity of large neural circuits. Yet, we are still only starting to understand how this high-dimensional complex system gives rise to functions such as processing ... -
The role of attention and adaptation in shaping cortical representations and the perception of abrupt changes in the visual environment
(2017-11-22)The visual system receives a wealth of visual information about objects with changing features in time. Attention is a mechanism allowing us to prioritize the processing of relevant information at the expense of other ... -
Neuronal representation and attentional modulation of space and feature information in primate vision
(2017-10-17)Visual perception lays the groundwork for many activities of animals and human. Decades of neuroscience research in vision also revealed much knowledge about the general computational principles of the brain. My dissertation ... -
On the Speed of Neuronal Populations
(2017-10-10)This thesis presents novel results in the areas of closed loop electrophysiology and neuronal population coding. This work begins by presenting the first known attempt to control the spike rate of a neuron or neurons using ... -
Genetic determination and layout rules of visual cortical architecture
(2017-08-30)The functional architecture of the primary visual cortex is set up by neurons that preferentially respond to visual stimuli with contours of a specific orientation in visual space. In primates and placental carnivores, ... -
Determination of the Dynamic Gain Function of Cortical Interneurons with distinct Electrical Types
(2017-04-25)In the living brain, individual neurons are constantly bombarded by thousands of synaptic inputs, which results in a fluctuating membrane potential. Neurons under such conditions are said to operate in a “fluctuation-driven ... -
Mathematical modeling of the structure and function of inner hair cell ribbon synapses
(2017-02-03)Information about the auditory world enters the mammalian brain through ribbon synapses of inner hair cells. Due to their fundamental role in auditory processing, these nanoscopic structures have recently received a lot ... -
Enhancing visual cortical plasticity in mice by enriching their environment: a combined imaging and behavioural study
(2017-02-01)Brain plasticity is important not only for normal brain functions like learning and memory, but is also crucial for recovery after injuries. It has been shown that the environment has a great influence on brain plasticity. ... -
Weakly Selective Training induces Specialization within Populations of Sensory Neurons
(2016-12-16)Many neurons in sensory pathways respond selectively to a narrow class of stimuli such as faces or specific communication calls. At the same time neural processing is robust to a large degree of natural variablity ...