Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Engel, Wolfgang Prof. Dr."
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The susceptibility of primordial germ cells to malignant transformation and isolation and characterization of members of a new gene family differentially expressed in invasive and non-invasive immortalized male germ cells
(2002-03-08)In this study, we examined the susceptibility of primordial germ cells (PGCs) to malignant transformation using a transgenic mouse model. In this model we used the simian virus 40 (SV40) ... -
Trim2 mutant mice as a model for cerebellar ataxia
(2003-11-25)In the frame of a large scale gene trap (GT) mutation screening focused on identification of novel genes involved in CNS development and function, a mouse GT line was characterized showing ... -
Untersuchung des transkriptionellen Mechanismus der Igf2- Überexpression in Patched-assoziierten Tumoren
(2006-12-06)For a better understanding of the formation and progression of Rhabdomyosarcoma (RMS) in heterocygous Ptch mutants, the present study was devoted to the transcriptional mechanisms of ... -
Untersuchungen zur Bedeutung der sal-ähnlichen Gene bei der Maus
(2002-01-11)The region-specific homeeotic gene spalt (sal) of Drosophila melanogaster is required for the specification of larval posterior head and anterior tail structures during embryogenesis. ... -
Untersuchungen zur Expression, Funktion und Regulation ausgewählter Gene der Insulinfamilie
(2006-10-16)In the present study, expression and functional analyses of two novel members of the insulin-superfamily, Insl5 and Insl6, were performed. Northern blot analysis on mRNA extracted from the ... -
Untersuchungen zur Regulation des Insl3 Gens
(2003-02-05)Insl3 is a testisspecific hormone which governs the development of the gubernaculum ligament needed for the migration of the embryonal testis to its adult scrotal position. We ... -
Über die funktionelle Analyse des murinen peroxisomalen Testis-spezifischen Gen 1 (Pxt1)
(2010-11-26)Mammalian spermatogenesis is a complex biological process by which diploid spermatogonia differentiate into specialized haploid spermatozoa. Regulation of male gametogenesis involves a ... -
Zur Expression und Funktion von Prm3: ein ungewöhnliches Protamin
(2003-10-28)In this work the Protamin3 (Prm3) gene as well as the resulting protein were characterized. Because this gene, along with the two other protamins (Prm1 and Prm2), is located in the same ...