Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Stülke, Jörg Prof. Dr."
Now showing items 1-20 of 20
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Functions of the Cold Shock Proteins in Bacillus Subtilis
(2021-07-09)RNA binding proteins are fundamental to the proper functioning of all cells. They are structural components in larger complexes such as ribosomes or regulate cellular processes that involve RNA such as transcription, ... -
Localization and Function of RNases in Bacillus subtilis
(2017-03-29)The ability to adapt to changing environmental conditions is essential for every organism to survive. In bacteria, this adaptation relies on the control of the mRNA synthesis, stability, and turnover, which allows the ... -
Characterization of proteins of the Asp23 protein family in Bacillus subtilis
(2017-02-07)The acetyl-CoA carboxylase (ACCase) catalyzes the production of malonyl-CoA, the precursor in fatty acid biosynthesis. In almost all organisms, this is a fundamental process since fatty acids are the main components of ... -
The development of an integrated database of the model organism Bacillus subtilis
(2016-01-25)In the era of “Omics” approaches, the available data is exponentially increasing and new methods must be invented to handle this data. For this purpose, databases store, maintain and provide the data, and algorithms ... -
Nebenwege des zentralen Kohlenstoffmetabolismus von Bacillus subtilis: Regulation der Methylglyoxalsynthase und der Zitratsynthase CitA
(2015-09-22)The phosphoenolpyruvate phosphotransferase system plays a crucial role in carbon metabolism of Bacillus subtilis. Besides uptake of different sugars the components of the PTS exert regulatory functions. This also accounts ... -
Novel virulence determinants in Mycoplasma pneumoniae: Contribution of transport systems and H2S production to viability and hemolysis
(2015-06-02)The human pathogen Mycoplasma pneumoniae is a remarkable minimal organism which primarily colonizes the human lung tissue. To reach distant infection sites, it probably also enters the blood stream. The Mycoplasma genome ... -
Untersuchung zur kohlenstoffabhängigen Wasserstoffperoxidproduktion und Virulenz in Mycoplasma pneumoniae und Mycoplasma genitalium
(2013-05-15)The human pathogens M. genitalium and M. pneumoniae use hydrogen peroxide as an important virulence factor. It could be shown that the glycerol-3-phosphate dehydrogenase (GlpD) is the key enzyme for the production of this ... -
Regulation der Aktivität und Lokalisation von Antiterminatorproteinen der BglG-Familie
(2012-11-12)The regulation of gene expression is essential for all bacteria and allows adapting to changing life conditions. Different transcription and translation factors have an important impact on gene regulation. The antermination ... -
An mRNA degradation complex in Bacillus subtilis
(2011-12-14)In every organism the degradation of mRNAs is a fundamental process. This step not only recycles nucleotides but also adjusts gene expression due to the availability of the mRNA templates. The main players in this process ... -
Der Einfluss der Glutamatdehydrogenasen auf die Verknüpfung des Kohlenstoff- und Stickstoffstoffwechsels in Bacillus subtilis
(2011-06-01)Glutamate is the central amino group donor for all nitrogen containing compounds in the cell. In the Gram-positive soil-dwelling bacterium Bacillus subtilis glutamate is exclusively synthesized ... -
Analysis of ether-à-go-go potassium channel (Eag1) splice variants in melanoma cells
(2011-05-03)The human ether-à-go-go potassium channel (hEag1) can be detected in adult brain and in both, tumor cell lines and primary tumors. The physiological function of this channel in the brain ... -
Pathogenicity of a minimal organism: Role of protein phosphorylation in Mycoplasma pneumoniae
(2010-12-17)Mycoplasma pneumoniae is a human pathogen that belongs to the Mollicutes, a group of bacteria with the smallest genomes that are capable of independent life. The reductive evolution of the ... -
Transcription in Mycoplasma pneumoniae
(2010-10-12)The human pathogen Mycoplasma pneumoniae has maintained only a small repertoire of genes putatively involved in transcription regulation. This reflects its adaption to a nutrient rich and ... -
Investigation of glycolysis in Bacillus subtilis
(2010-05-19)Bacillus subtilis is a model organism for Gram-positive bacteria and object for biotechnological applications. The extensive investigation of this bacterium makes it one of the best studied ... -
Regulation of glucosamine-6-phosphate synthase synthesis by a hierarchical acting cascade composed of two small regulatory RNAs in <i>Escherichia coli</i>.
(2010-04-14)Amino sugars are essential for the biosynthesis of the bacterial cell wall and of lipopolysaccharides. The enzyme glucosamine-6-phosphate synthase (GlmS) catalyzes the formation of ... -
Untersuchung der Spezifität von Antiterminationsproteinen in Bacillus subtilis
(2009-02-20)Regulatory systems often evolve by duplication of ancestral systems and subsequent specialization of the components of the novel signal transduction systems. In the Gram-positive bacterium ... -
Glycerolmetabolismus und Pathogenität von <i>Mycoplasma pneumoniae</i>
(2008-06-03)Mycoplasma pneumoniae, the causative agent of atypical pneumonia, is able to use glucose and fructose as well as glycerol as sole carbon source. Glycerol is taken up by facilitated diffusion ... -
Carbon Catabolism in <i>Bacillus subtilis</i>: Global and Molecular Views on the Control of Gene Expression
(2007-11-12)The soil bacterium B. subtilis is exposed to frequently changing environmental conditions. Moreover, in its natural habitat, B. subtilis is surrounded by numerous microorganisms ... -
Regulation der Glutamatsynthese in Bacillus subtilis durch die Glutamatdehydrogenase RocG und das Aktivatorprotein GltC
(2006-11-20)Bacillus subtilis is able to utilize a huge number of carbon sources. For efficient utilization of a carbon source both, carbon and nitrogen metabolism, have to be well coordinated. ... -
Regulation of HPr phosphorylation in Mycoplasma pneumoniae
(2006-11-08)The genome of the mollicute Mycoplasma pneumoniae contains only 688 genes. Among the very few regulatory proteins retained is the HPr kinase/phosphorylase (HPrK/P) of the phosphoenolpyruvate:sugar ...