Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Heimel, Kai Prof. Dr."
Now showing items 1-19 of 19
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The complex formation of RNase P and RNase MRP in Saccharomyces cerevisiae
(2024-03-06)Ribonucleoproteins comprise a class of complexes that consist of RNAs and proteins. Riobozymes are catalytically active ribonucleoproteins that play a key role in the maturation of various RNAs. A prominent example is ... -
Morphological and molecular adaptation of Aspergillus niger to simulated spaceflight and Mars-like conditions
(2021-10-18)The International Space Station (ISS) is an indoor-closed environment in Low Earth Orbit (LEO). Outside of the ISS, radiation is the most challenging factor outside. In turn, inside the ISS, spaceflight microgravity is the ... -
Impact of rainforest conversion: How prokaryotic communities respond to anthropogenic land use changes
(2020-12-03)In this thesis, the impact of rainforest conversion to the managed land use systems jungle rubber, rubber plantation and oil palm plantation on structure and function of soil microbial communities was investigated. The ... -
Developmental regulators and secreted effector molecules of the fungal pathogen Verticillium spp.
(2020-09-29)The haploid Verticillium dahliae and the allodiploid V. longisporum are two filamentous fungal pathogens, which colonize the plant vascular system of a broad host range including important crops. They survive outside of ... -
Assessment of antibiotic resistance in soil and its link to different land use types and intensities
(2020-07-15)Nowadays, bacterial infections pose a serious risk for human health again, due to multi-resistant pathogens insensitive to antibiotic treatment. Some of the antibiotic resistance genes (ARGs) carried by these pathogens ... -
Interplay of Verticillium signaling genes favoring beneficial or detrimental outcomes in interactions with plant hosts
(2020-07-14)Verticillia and their plant hosts both contribute to pathogenesis as a consequence of their interaction. Evolution-driven genome extension includes hybridization, resulting in amphidiploid species as the rapeseed pathogen ... -
Variability of biofilm formation in Candida glabrata and Candida parapsilosis and its consequences on the infection process
(2019-08-30)The prevalence of Candida species has increased in the last two decades, becoming the third to fourth most common cause of infections in hospitals. In general, Candida spp. are opportunistic pathogens found as commensals ... -
Characterization of a novel regulator of the unfolded protein response in Ustilago maydis and mammals
(2019-07-16)The endoplasmic reticulum (ER) is an eukaryotic organelle which is the entry point into the secretory pathway and responsible for protein synthesis and processing. The amount of proteins to be folded in the ER lumen is ... -
Analysis of Clp1-dependent UPR modulation in Ustilago maydis
(2019-06-13)The unfolded protein response (UPR) is a conserved signaling pathway, that is present in all eukaryotic cells and ensures endoplasmic reticulum (ER) homeostasis under stress conditions. In the phytopathogenic fungus U. ... -
Phylogenetic and functional diversity of soil prokaryotic communities in temperate deciduous forests with different tree species
(2019-04-30)Forest ecosystems provide an important contribution to global carbon storage through processes mediated by trees. As the dominant forest vegetation, trees largely drive primary productivity and mediate the flow of aboveground ... -
Verticillium dahliae transcription factors Som1 and Vta3 control microsclerotia formation and sequential steps of plant root penetration and colonisation to induce disease
(2018-10-12)Verticillium dahliae belongs to the soil-borne ascomycete fungi. It causes wilt diseases and early senescence in more than 200 plant species including economically important crops. It can exist in the soil without a host ... -
Analyse der UPR vermittelten Stressantwort und ihrer Funktion während der biotrophen Entwicklung von<i> Ustilago maydis</i>
(2016-12-09)The unfolded protein response (UPR) is a conserved eukaryotic signaling network that is activated by accumulation of misfolded proteins in the endoplasmic reticulum (ER) to ensure protein homeostasis. In the baker's yeast ... -
Stress Response SCF Ubiquitin Ligase F box Protein Fbx15 Controls Nuclear Co repressor Localization and Virulence of the Opportunistic Human Fungal Pathogen Aspergillus fumigatus
(2016-09-06)Aspergillus fumigatus is the most prevalent cause for pulmonary infections in immuno-compromised patients. Virulence factors are often linked to developmental control mechanisms, which are often identified in the closely ... -
Prokaryotic Biodiversity of Lonar Meteorite Crater Soda Lake Sediment and Community Dynamics During Microenvironmental pH Homeostasis by Metagenomics
(2016-08-24)This thesis is on the Archaea and Bacteria from a hypersaline hyperalkaline lake sediment of a meteorite impact crater named Lonar. We have surveyed the active and the total biodiversity of the sediment from Lonar. We have ... -
Phosphorylation dependent stability control of the deneddylase DenA and its impact on Aspergillus nidulans development
(2016-04-05)Summary Malfunctioning protein degradation in higher eukaryotes is associated with numerous diseases, including neurodegenerative disorders and cancer. Understanding regulation mechanisms of protein degradation is thus ... -
Analyse und Charakterisierung regulatorischer Vorgänge in Bacillus licheniformis
(2015-05-08)Analysis of RNA-Seq data in a genome context sensitive approach to identify known and novel RNA-regulatory elements and events applied by Bacillus licheniformis DSM13 to adapt its physiology to a productive fermentation. ... -
Analyses of the Life Cycle of TLC1 and the Nuclear RNA Quality Control System in Saccharomyces cerevisiae
(2015-04-24)During genome replication, chromosomes undergo a progressive shortening of their ends. To counteract this loss, a complex named telomerase functions as a reverse transcriptase to elongate telomeres. In Saccharomyces ... -
Identifizierung schutzvermittelnder Antigene von Aspergillus fumigatus für eine Impfstoffentwicklung zur Verhütung invasiver Aspergillosen bei Leukämie-Patienten
(2015-01-23)A.fumigatus is the most common cause of invasive, usually fatal aspergillosis in severely immunocompromised patients. A natural resistance to the fungus is mediated by the innate immune system. Additionally, an acquired ... -
Impact of plant species, N fertilization and ecosystem engineers on the structure and function of soil microbial communities
(2014-02-26)Soil microbial communities are directly and indirectly influenced by a complex system of cross-interactions between different biotic and abiotic factors influencing each other, such as plant species and their respective ...