Browsing Human- und Zahnmedizin by Referee "Gaedcke, Jochen Prof. Dr."
Now showing items 1-14 of 14
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Finite element analysis investigation of positive reduction in the femoral neck fracture
(2025-02-05)Aim Gotfried positive reduction offers an alternative strategy for femoral neck fracture (FNF) when achieving anatomical reduction is challenging. However, quantifying positive reduction and assessing the potential issues ... -
Retrospektive Studie zur Erhebung von Risiko-Scores zur frühzeitigen Prädiktion von Post-Polypektomie-Blutungen im Gastrointestinaltrakt
(2025-01-06)Post-polypectomy bleeding (PPB) is a common and clinically relevant complication following gastrointestinal polypectomy. Their severity ranges from mild to severe events. Nervertheless, accurate prediction in clinical ... -
Inzidenz von Arrhythmien nach Leberoperationen: Risikofaktoren für das Auftreten von postoperativen Herzrhythmusstörungen und deren Einfluss auf den postoperativen Verlauf von Patienten
(2024-12-13)Not only after cardiac or thoracic operations, but also after abdominal operations such as liver resections, cardiac arrhythmias (CA) regularly occur as a postoperative complication during the inpatient course. This is ... -
Inzidenz und Auswirkungen von Arrhythmien nach viszeralchirurgischen Eingriffen für Operationen am unteren Gastrointestinaltrakt
(2024-07-26)The occurrence of arrhythmias in the postoperative course is not uncommon, but in visceral surgery, particularly in the lower gastrointestinal tract, it is not as frequently encountered or investigated as it is in cardiac ... -
Das Ausmaß der Fibrose beim duktalen Pankreaskopfkarzinom korreliert mit der Prognose
(2022-11-29)Extension of fibrosis correlates with the prognosis for pancreatic ductal adenocarcinoma (PDA) Müller J, Kitz J, Bernhard M, Azizian A, Grade M, Ströbel P, Ghadimi M, Gaedcke J. Introduction For patients with PDA ... -
Einfluss verschiedener KRAS-Mutationen auf das Ansprechen von kolorektalen Zellen auf eine 5-Fluorouracil-basierende Radiochemotherapie in Anwesenheit von Rezeptortyrosinkinase-Inhibitoren
(2022-02-14)Aims: Mutations of the proto-oncogene KRAS are supposed to lead to an increased activity of KRAS inducing a constitutive activation of the downstream MAPK signaling pathway. The aim of the work was to investigate the ... -
Evaluation von Ramucirumab und FOLFIRI bezüglich Wirksamkeit und Sicherheit in der palliativen Therapie des Magenkarzinoms
(2021-11-26)Advanced gastric cancer is an epithelial neoplasia of the gastrointestinal tract in which metastasis has often occurred at the time of diagnosis. The treatment options in this palliative situation are mostly drug-based and ... -
Der Tumorsuppressor p53 reguliert HSF1 im Modell des kolorektalen Karzinoms
(2021-07-13)The regulator of the cellular stress response programm HSF1 is regulated by the tumor suppressor p53 by inhibition of the phosphorylation of Ser326. This reduces HSF1 transcriptional activity and halts the stress response ... -
Evaluation der sonographischen Gallenblasenwanddicke als neuer nicht-invasiver Marker für das Vorliegen von Ösophagusvarizen
(2020-10-08)Background: The mortality due to hemorrhage of esophageal varices (EV) is still high. The predominant cause for EV is liver cirrhosis, which has a high prevalence in Western Europe. Therefore, non-invasive screening markers ... -
Klinische Bedeutung des abführenden Schenkels im Vergleich zur Rektoskopie in der Diagnostik vor Ileostomarückverlagerung
(2020-07-23)In the context of visceral resections, the creation of an artificial bowel outlet (stoma) may be necessary. Among other aspects, the protective double loop ileostomy has become established. One lumen, which conveys the ... -
Diagnostische und therapeutische Aspekte des Narrow Band Imaging beim Harnblasenkarzinom
(2020-01-31)BACKGROUND: Narrow Band Imaging (NBI) is an easy endoscopic procedure introduced to be beneficial to common white light cystoscopy by using specific bands (hemoglobin absorption maxima) of white light and therefore showing ... -
Einfluss von microRNAs auf die Sensibilität von kolorektalen Tumorzellen gegenüber einer 5-FU-basierten Radiochemotherapie
(2019-08-29)The clinical course of comparable patients (same tumor stage, age, gender and comparable histopathological parameters) suffering from rectal cancer can vary widely. The range of response rates to neoadjuvant chemoradiation ... -
Diagnostische Varianzen bei Ösophagus- und Magentumoren
(2019-04-02)Oesophageal and gastric carcinomas are within the twenty most common malignancy-related causes of death in Germany. Since early symptoms are rare, the diagnosis is mainly made in late stages. However, to plan therapies ... -
Prädiktive Biomarker für die Entwicklung von high grade acute organ toxicity im Rahmen der Radiochemotherapie bei Patienten mit Kopf-Hals-Tumoren
(2017-11-22)The treatment of head and neck cancers by radiochemotherapy often leads to high grade acute organ toxicity (HGAOT). These side effects impair the patients’ quality of life as well as the local tumor control as they can ...