Dokumente Human- und Zahnmedizin nach Gutachter "Oppermann, Martin Prof. Dr."
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Allergische und irritative Kontaktdermatitis in Filaggrin- und Hornerin-defizienten Mäusen
(2020-10-13)The two epithelial structural proteins filaggrin (Flg) and hornerin (Hrnr) play a major role in upholding the integrity of the skin barrier function. Loss-of-function mutations in these genes cause an epidermal barrier ... -
Analyse der Beschwerden von Patienten mit iatrogenem Hypoparathyreoidismus
(2013-03-28)Introduction Persistent postsurgical iatrogenic hypoparathyroidism is a significant problem after thyroid surgery for 0.5 to 4 % of patients. Despite adequate therapy with calcium and vitamin D well-being is not easily ... -
Analyse der Expression von Chemokinen und Chemokinrezeptoren in Kopf-Hals-Tumorzellen
(2018-03-08)Radiotherapy plays an important role in the treatment of malignant head and neck tumors. Chemokines are chemotactic cytokines, which can induce tumor proliferation as well as metastasis, although the influence of chemokines ... -
Analyse der Operations-Verfahren bei Reablatio retinae ohne Proliferative Vitreoretinopathie nach primärer Buckelchirurgie - pars-plana-Vitrektomie versus Buckelrevision-
(2013-11-13)We retrospectively analyzed 79 eyes, which developed a rhegmathogenous retinal redetachment without PVR after primary buckle-surgery during the years 1994 – 2006, which were treated at the eye clinic of the University of ... -
Analyse der optimalen Stimulationstemperatur zur Messung der Schmerztoleranz
(2013-07-15)Especially in pain research plays a recording of pain tolerance thresholds a major role. The aim of our study was was to develop the ideal temperature stimulationof measurement of pain tolerance. These methods have in ... -
Analyse der Proteinexpression zur Untersuchung der physiologischen Funktion des zellulären Prionproteins (PrPc)
(2012-01-04)The definite physiological role of the cellular prion protein (PrPc) remains still unclear. On the one hand there is ample in vitro and in vivo evidence suggesting a neuroprotective role ... -
Die Analyse der Rolle von STAT6 im klassischen Hodgkin-Lymphom
(2011-11-14)Hodgkin`s lymphoma is a common malignancie oft the lymphsystem.The role of STAT6 (signal transducer and activator of transcription) in Hodgkin´s lymphoma is not entirely revealed. The ... -
Analyse der Spätergebnisse und Ganganalyse bei Patienten nach operativ versorgter Fraktur oder Luxationsfraktur in den Lisfranc- und Chopartgelenklinien
(2016-04-12)Tarsal injuries often lead to patient disability. Since these injuries - especially dislocations of the Chopart and Lisfranc joint line – are rare and frequently associated with multiple more severe traumas, they still ... -
Analyse des antifibrotischen Potenzials der betaadrenergen Signalkaskade und des PKA-Effektors Protein-Phosphatase-Inhibitor-1
(2017-05-17)The fibrotic remodeling of the heart appears in several cardiac diseases. Especially fibroblasts, which are known as the tissue producing cells in the heart, contribute to this process. Interacting with cardiomyocytes they ... -
Analyse des PEX1-Gens bei Patienten mit Zellweger-Syndrom: Identifikation einer neuen Deletion und Untersuchung von Polymorphismen in der 5'-untranslatierten Region
(2011-07-14)Zellweger spectrum disorders are autosomal recessive peroxisomal metabolic diseases. Mutations in the PEX1 gene are the most common cause. This thesis deals with the analysis of the PEX1 ... -
Analyse neuropsychologischer Ausfallprofile bei zerebraler Mikroangiopathie
(2013-09-27)Introduction As the population gets older dementia as a disease of the elderly has to be faced more often. After Alzheimer's dementia (AD) cerebral small vessel disease (CSVD) is the most frequent cause of cognitive ... -
Analyse organoprotektiver Effekte der renalen Denervation zur Behandlung therapierefraktärer arterieller Hypertonie
(2019-04-10)Background: The effectivity of renal denervation relating to the reduction of arterial hypertension could be demonstrated in previous studies. The interventional procedure affects the sympathetic overactivity, a crucial ... -
Analyse organoprotektiver Effekte durch eine Barorezeptorstimulationstherapie zur Behandlung der Therapie-refraktären arteriellen Hypertonie
(2017-03-03)Cardiovascular disease accounts for 50% of the causes of death. The arterial hypertension (aHTN) is the main risk factor for cardiovascular morbidity and mortality and shows a prevalence of almost 40% in the European ... -
Analyse transgener Mauslinien mit zelltypspezifischer Expression fluoreszenter Proteine als Modelle für akute Hirntraumata
(2010-10-12)Within the thesis presented in here two mouse lines (PRDA & PRDB) were characterized. In these lines the fluorescent protein DsRed was expressed under the control of the PLP promotor. Both ... -
Analyse von Effizienz und Komplikationen der Lipidaphereselangzeittherapie
(2011-02-23)Retrospective analysis over 20 years on 38 patients, which were treated with lipid apheresis. Efficiency, compatibleness and adverse effects of the procedures HELP, DALI immunadsorption and ... -
Analyse von Mikrosatelliteninstabilität und hMSH2-Expression bei Patienten mit akuter myeloischer Leukämie
(2017-06-12)Acute myeloid leukemia, the most common acute leukemia in adults, is a malignant, genetically heterogeneous, clonal disorder, which is based on haemopoietic progenitor cells with a disrupted ability of self-renewal, ... -
Analyse von Proteinen und deren Elimination durch drei verschiedene extrakorporale Therapieverfahren der LDL-Apherese bei Patienten mit familiärer Hypercholesterinämie mittels Proteomics-Methoden
(2010-10-20)Background: The aim of our study was the analysis of proteins filtered through several ways of LDL-apharesis by proteomic methods. In order to do so we examined patients with familiar ... -
Analysis of catecholamine-induced beta-adrenergic signaling in TTS by patient-specific pluripotent stem cell-derived cardiomyocytes
(2020-04-06)Takotsubo syndrome (TTS) is a heart disease characterized by left ventricular dysfunction. Its clinical presentation frequently mimics acute myocardial infarction and the disease mainly occurs in postmenopausal women after ... -
Angehörige von Tumorpatienten in der spezialisierten stationären Palliativversorgung - Lebenssinn und bedeutsame Lebensbereiche
(2020-07-23)Tumor diseases are the second most common cause of death headed by cardiovascular diseases. Approximately one in four deaths is caused by cancer. Palliative care pursues the unit of care concept treating family caregivers ... -
Angstausprägung, Inflammation und neurohumorale Aktivierung bei systolischer und diastolischer Dysfunktion
(2014-02-28)Study about assumed anxiety-resolving factors on patients with diastolic and systolic dysfunction. The evaluated factors are MRproANP, BNP, NTproANP and hsCRP.