Browsing Human- und Zahnmedizin by Referee "Wilting, Jörg Prof. Dr."
Now showing items 1-20 of 29
-
In-ovo-Untersuchungen zum Zellstoffwechsel des Hodgkin-Lymphoms
(2025-02-27)Excellent survival rates of patients with Hodgkin lymphoma (HL), a malignant neoplasm of the lymphatic system, may be compromised by acute and long-term toxicities, including infertility, cardiovascular damage, and secondary ... -
Interaktion von Lymphomzellen und Makrophagen in einem in-ovo-Modell
(2024-11-21)In recent years, there has been increasing evidence that the tumor microenvironment plays a varying but important role in the development of lymphomas in different types of lymphoma and influences the success of treatment. ... -
Vergleich der einseitigen und zweiseitigen Osteotomie im osteoporotischen Rattenmodell
(2024-09-06)The aim of this work was to heal a unilateral (UL) with bilateral (BL) osteotomy in the osteoporotic rat model. The assumption was that a UL osteotomy would result in an uneven Stress on the limbs occurs and this ... -
Knochenregeneration von akuten Critical-size-Defekten in der Mandibula des Göttinger Minischweins durch die kombinierte Freisetzung von rhBMP-2 und rhVEGF165 aus einem PDLLA/CaCO3-Komposit
(2023-06-15)The present study was designed to clarify whether the combined release of the growth factors rhBMP-2 and rhVEGF165 from PDLLA/CaCO3 composite material results in equivalent new bone formation to loading the carrier materials ... -
Ursachen und Häufigkeiten des Skorbuts in den präkolumbischen Kinderpopulationen von Teotihuacán (Mexiko) und Jaina (Mexiko) sowie aus dem nordamerikanischen Piedmont (USA)
(2023-06-14)The dissertation centers around possible etiologies and occurrence of infantile scurvy (also known as Moller-Barlow-disease) in three archaeological sites of Teotihuácan (Mexico), Jaina (Mexico) and the North American ... -
Der Einfluss der Induktion von Tumornekrosefaktor α und Transforming-Growth-Factor β auf die epithelial-mesenchymale Transition oraler Plattenepithelkarzinome im CAM-Assay
(2021-02-09)Introduction: The oral squamous cell carcinoma (OSCC) belongs to one of the highest malignant carcinomas of the upper aerodigestive passages. The aim of this study was to see if the fresh OSCC tumor samples could be used ... -
Untersuchung spezifischer Inhibitoren der PI3K-Signalkaskade zur Therapie des Lymphangioms
(2020-07-06)Lymphatic malformations (LM; lymphangiomas) are benign congenital malformation disorders of the lymphatic system and are characterized by cystic lymphatic enlargements. A distinction is made between the macrocystic, ... -
Eine prospektive Studie zur operativen Therapie des Beinlymphödems
(2020-01-08)Secondary lymphedema of the leg is a chronic and progressive disease which cannot be healed. In the industrialized countries the most frequent course of secondary lymphedema of the leg is preceding tumor surgery with ... -
Vergleichende Analysen von drei verschiedenen Burkitt-Lymphom-Zelllinien im CAM-Xenograft-Modell unter besonderer Berücksichtigung des Transkriptionsfaktors LEF1
(2018-10-15)Burkitt's lymphoma (BL) is a highly malignant, aggressive non-Hodgkin's lymphoma. The hallmark of this lymphoma is the characteristic MYC translocation, which together with other mutations can lead to the development of a ... -
Rekrutierung von Immunzellen in das perivaskuläre Fettgewebe bei Adipositas – Bedeutung von Leptin
(2018-06-06)Obesity is a well-known risk factor for the development of atherosclerosis and cardiovascular diseases and is associated with hyperleptinemia and a proinflammatory state. Besides the effect of visceral adipose tissue, newer ... -
Proliferationsuntersuchungen zur Entwicklung des Lymphgefäßsystems bei Wnt5a-transgenen Mäusen
(2018-04-27)Wnt5a is a secreted glycoprotein and represents one of the 19 members of the human WNT-gene-family, which regulate embryonic development. In contrast to most other members of the Wnt-family, Wnt5a also is a regulator of ... -
Untersuchungen zur Angiogenese des Burkitt-Lymphoms unter besonderer Berücksichtigung des Lymphocyte enhancer-binding factor-1
(2017-11-03)Burkitt´s Lymphoma (BL), derived from abnormal germinal center B cells, is a highly malignant, aggressive Non-Hodgkins´s lymphoma. Aim of our study was to dissect the functional role of the transcription factor Lymphocyte ... -
Angiopoetin-1 im Kontext von EPCs-vermittelter Nephroprotektion nach akuter renaler Ischämie
(2017-09-19)Aim Acute kidney injury significantly worsens the prognosis of hospitalized patients. Endothelial progenitor cells have been proven as effective tool for AKI prevention in mice. Pharmacological EPC precondition-ing may ... -
Die Bedeutung der glomerulären Basalmembrankomponente Nidogen-1 bei podozytären Erkrankungen der Niere
(2017-05-22)The basement membrane composition of the glomeruli is an important factor in the pathogenesis of many renal diseases. The understanding of the interactions of the BM components and the pathogenesis of glomerular renal ... -
Nidogen-2 in der Pathogenese Kollagen IV-assoziierter Nephropathien bei zusätzlicher Podocin-Mutation
(2016-11-21)Collagen IV-related nephropathies are hereditary diseases affecting the glomerular basement membrane. Homozygous aberrations of COL4A3 or COL4A4 gene or X-linked mutations of COL4A5 gene are responsible for Alport syndrome ... -
Einfluss von LEF1 auf das Tumorwachstum im Burkitt-Lymphom-Xenograft-Modell
(2016-11-18)Because of the limited knowledge about the biology of the highly aggressive Burkitt- Lymphoma is still possible in many cases no cure, it is all the more important, Possible therapeutic approaches. One possible starting ... -
Untersuchung der systemischen und parakrinen Wirkungen von Leptin auf die Neointimabildung nach experimenteller Gefäßverletzung im Mausmodell
(2016-04-04)Obesity is a very good known risk factor of atherothrombotic complications of the heart and the vessel system. Additionally growing bodyweight and elevated mass of the perivascular adipose tissue (PVAT) and visceral adipose ... -
Die lymphatischen Abflusswege von Gehirn und Hypophyse im Mausmodell
(2016-02-23)The present work primarily conduced to the observation whether there are comparable lympahtic vessels in the brain as in the rest of the body and if applying where these drain off. Therefore for larger proteins and molecules ... -
Der Einfluss des DDR1+/-/NPHS2+/R140Q-Genotyps auf die Interaktion zwischen glomerulärer Basalmembran und Schlitzmembran im Tiermodell
(2014-05-09)Heterozygous Alport mutations of type IV collagen genes lead to Benign Familial Hematuria without excessive proteinruia or progression to end stage kidney disease. Heterozygous polymorphisms of the podocin-gene also do not ... -
Morphometrischer Vergleich der Gewebeveränderung bei Weichgewebedissektion mit dem Ultraschallskalpell und monopolarer Elektrokoagulation
(2014-02-04)Background Ultrasonic scalpel (UC) and monopolar electrocautery (ME) are common tools for soft tissue dissection. However, morphological data on the related tissue alteration are discordant. We developed an automatic ...