Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Stülke, Jörg Prof. Dr."
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Investigation of glycolysis in Bacillus subtilis
(2010-05-19)Bacillus subtilis is a model organism for Gram-positive bacteria and object for biotechnological applications. The extensive investigation of this bacterium makes it one of the best studied ... -
Mechanismen der Inhibierung von Wirtszellapoptose durch <i>Toxoplasma gondii</i>
(2009-02-02)Toxoplasma gondii is an obligate intracellular apicomplexan parasite. Due to its broad spectrum of hosts and its lifelong persistence in the host it is one of the most successful parasites. ... -
Metabolismus und Biomineralisation in anaerob Methan-oxidierenden Lebensgemeinschaften
(2011-03-15)Anaerobic oxidation of methane (AOM) is recognized as one key process of methane consumption in oceans. According to phylogenetic and metagenomic analyses, the process is carried out by ... -
Monitoring von Membranen und membrangebundenen Dehydrogenasen in Essigsäurebakterien
(2013-11-20)The occurrence of intracytoplasmic membranes (ICM) in Gluconobacter oxydans was first described by Claus et al. in 1975. The presence of the ICM was observed during the early stationary growth phase. It was proposed, that ... -
Novel virulence determinants in Mycoplasma pneumoniae: Contribution of transport systems and H2S production to viability and hemolysis
(2015-06-02)The human pathogen Mycoplasma pneumoniae is a remarkable minimal organism which primarily colonizes the human lung tissue. To reach distant infection sites, it probably also enters the blood stream. The Mycoplasma genome ... -
Die parasitophore Vakuole des Mikrosporidiums Encephalitozoon cuniculi: Biogenese und Metabolitaustausch
(2008-11-12)Microsporidia possess a unique invasion mechanism, which is based on the explosive extrusion of a hollow tube, the so called polar tube, from the microsporidian spore. The common infection ... -
Pathogenicity of a minimal organism: Role of protein phosphorylation in Mycoplasma pneumoniae
(2010-12-17)Mycoplasma pneumoniae is a human pathogen that belongs to the Mollicutes, a group of bacteria with the smallest genomes that are capable of independent life. The reductive evolution of the ... -
Regulation der Aktivität und Lokalisation von Antiterminatorproteinen der BglG-Familie
(2012-11-12)The regulation of gene expression is essential for all bacteria and allows adapting to changing life conditions. Different transcription and translation factors have an important impact on gene regulation. The antermination ... -
Regulation der Glutamatsynthese in Bacillus subtilis durch die Glutamatdehydrogenase RocG und das Aktivatorprotein GltC
(2006-11-20)Bacillus subtilis is able to utilize a huge number of carbon sources. For efficient utilization of a carbon source both, carbon and nitrogen metabolism, have to be well coordinated. ... -
Regulation der Synthese der Glukosamin-6-Phosphat Synthase GlmS in Escherichia coli durch das neuartige Protein YhbJ
(2009-03-19)Amino sugars are essential building blocks of life. In bacteria, they are mainly used as precursors for the biosynthesis of the cell wall. Their de novo synthesis starts with the transformation ... -
Regulation of HPr phosphorylation in Mycoplasma pneumoniae
(2006-11-08)The genome of the mollicute Mycoplasma pneumoniae contains only 688 genes. Among the very few regulatory proteins retained is the HPr kinase/phosphorylase (HPrK/P) of the phosphoenolpyruvate:sugar ... -
Die regulatorischen Funktionen des paralogen Phosphotransferase Systems (PTSNtr) in Escherichia coli.
(2012-07-11)Das Phosphoenolpyruvat:Kohlenhydrat Phosphotransferase System (Transport-PTS) ist das bedeutendste System in Bakterien um organische Kohlenstoffverbindungen in die Zelle aufzunehmen. Ebenso koordiniert es die Aufnahme und ... -
Structure-based Search for novel c-di-AMP Synthase Inhibiting Fragments
(2023-03-24)One of the major threats for the global health system is the increasing number of antibiotic resistant bacterial strains. The misuse of antibiotics during the Covid pandemic aggravates these problems. Therefore, the ... -
The development of an integrated database of the model organism Bacillus subtilis
(2016-01-25)In the era of “Omics” approaches, the available data is exponentially increasing and new methods must be invented to handle this data. For this purpose, databases store, maintain and provide the data, and algorithms ... -
Untersuchung der Spezifität von Antiterminationsproteinen in Bacillus subtilis
(2009-02-20)Regulatory systems often evolve by duplication of ancestral systems and subsequent specialization of the components of the novel signal transduction systems. In the Gram-positive bacterium ... -
Untersuchung zur kohlenstoffabhängigen Wasserstoffperoxidproduktion und Virulenz in Mycoplasma pneumoniae und Mycoplasma genitalium
(2013-05-15)The human pathogens M. genitalium and M. pneumoniae use hydrogen peroxide as an important virulence factor. It could be shown that the glycerol-3-phosphate dehydrogenase (GlpD) is the key enzyme for the production of this ... -
Untersuchungen zur Inhibierung der Expression der Poly(ADP-ribose)Polymerase (PARP) nach Infektion mit Toxoplasma gondii
(2008-11-17)Toxoplasma gondii is a world wide spread and obligate intracellular protozoan parasite, which induces mostly asymptomatic, lifelong persisting infections in humans. Furthermore, it is an ... -
Zelltyp-spezifische Interaktionen von Toxoplasma gondii und murinen Skelettmuskelzellen in vitro
(2014-06-26)Toxoplasma gondii is one of the most common intracellular protozoan parasites worldwide and an important human pathogen. Its life cycle includes three stages: sporozoites, tachyzoites and bradyzoites. While sporozoites are ...