Dokumente Zentren & Graduiertenschulen nach Titel
Anzeige 544-563 von 1254
-
Lab-on-chip design to characterize pore-spanning lipid bilayers
(2013-11-26)A powerful approach to study membrane proteins is the reconstitution in model membranes. Methods for arti cial bilayer formation are e.g. membranes on a solid support, or the classical BLM. In this project, the focus was ... -
Landscape effects on predator activity and nest predation in grey partridges Perdix perdix
(2023-04-14)Europe's agricultural landscapes used to be home to a wide variety of plants and wildlife that have adapted to these open, cultivated landscapes. Following the onset of large-scale agricultural intensification in the ... -
Leaf Venation Networks
(2016-02-23)Understanding the leaf venation network is a multifaceted endeavor that requires tools from several fields of study. This thesis addresses a broad range of questions, all guided by a central theme: “How does the geometry ... -
Limitations in Global Information on Species Occurrences
(2016-02-02)Detailed information on species distributions is crucial to answering central questions in ecology, evolutionary biology and biogeography and for effectively allocating conservation resources among regions. Huge numbers ... -
Linking senses: the genetics of Drosophila larval chordotonal organs
(2018-08-06)Sensory systems have evolved in all organisms to detect changes in the environment or their internal state. Even though they are essential for fitness and survival, their phylogenisis is still unclear. The protosensory ... -
Lipid dependent interactions of biomimetic membrane models with the ENTH domain of epsin
(2020-02-05)Membrane remodeling processes during endocytosis are highly regulated by the protein-protein and protein-membrane interactions. In clathrin-mediated endocyto-sis (CME) binding of the protein epsin to its receptor lipid ... -
Lipid organisation and dynamics in the myelin membrane sheets
(2014-07-25)Myelin is a unique lipid-enriched membrane, produced by oligodendrocytes in the central nervous system, that is enwrapped around axons in the multilayered fashion to ensure a swift saltatory conduction of the neuronal ... -
Lipids in plant development and stress responses
(2023-08-22)In plant cells, lipids are important components of cellular membranes. There, they act as structure-forming and/or signal-transmitting elements. As signals, lipids are landmarks and thereby important regulators, for example ... -
Live imaging of autoimmune responses in distinct milieus of the central nervous system
(2013-08-28)Multiple sclerosis (MS) is the most common inflammatory disease of the central nervous system (CNS). Even though it is considered to be a classical demyelinating disease, an increasing body of evidence also demonstrates ... -
Localisation and function of Slam in the early Drosophila embryo
(2014-11-06)Embryogenesis of many insects starts with a syncytial stage characterised by 13 rapid nuclear divisions. During the following interphase, the plasma membrane of the embryo invaginates between each nucleus to give rise to ... -
Long-Term Temporal Dynamics of Synaptic Vesicles
(2017-09-11)Neurotransmission requires the release of neurotransmitters from synaptic vesicles. This occurs via fusion of the vesicle to the pre-synaptic membrane upon stimulation. However, not all synaptic vesicles are equally ... -
Long-term vegetation dynamics along altitudinal and longitudinal gradients in the Hyrcanian forest region (northern Iran)
(2022-12-14)As an Arcto-Tertiary species refugium, the Hyrcanian forest region of Iran, may play an important role in investigating paleoclimatic and palaeoecological changes. This narrow belt, located between the biggest lake of the ... -
Lysosomal and mitochondrial crosstalk: the role of lysosomal signaling on mitochondrial biogenesis and function
(2018-11-15)Defects in metabolism result in various diseases, with neurodegeneration being one of the most prevalent consequences. Mitochondria and lysosomes are long known to be fundamental for cellular metabolism. In addition to ... -
Machine learning classification of patients with major depressive disorder and healthy controls using magnetic resonance imaging data
(2023-04-19)Major depressive disorder (MDD) is a prevalent and complex psychiatric disorder affecting more than 300 million people worldwide. It is characterized by a highly heterogeneous spectrum of symptoms, including low mood and ... -
Mad2l2 as a safeguard for open chromatin in embryonic stem cells
(2016-08-08)Open chromatin is induced locally during the repair of DNA double-strand breaks when a cascade of protein recruitments and modifications is triggered. This "ATM cascade" includes components like the Mrn complex, ATM kinase, ... -
Mad2l2 in primordial germ cell development and pluripotency
(2013-11-18)The development of primordial germ cells (PGCs) involves several waves of epigenetic reprogramming. A major step is the transition from the stably suppressive histone modification H3K9me2 to the more flexible, still ... -
Maintenance of glutamate homeostasis in Bacillus subtilis by complex regulatory systems and genomic adaptation
(2017-10-16)The Gram-positive model organism Bacillus subtilis lives in the soil and must cope with a constantly changing environment. Glutamate plays an important role in cellular metabolism, because it is the major amino group ... -
Manipulating co-regulators of RUNX2 and SOX9 to enhance the chondrogenic potential of chondrogenic progenitor cells in osteoarthritis
(2020-12-11)Osteoarthritis (OA) is a degenerative disease of the joint leading to the degradation of the articular cartilage. Current therapies cannot halt or reverse the disease, leading to a severe impact on life quality accompanied ... -
Manipulating neuronal communication by using low-intensity repetitive transcranial magnetic stimulation combined with electroencephalogram
(2021-11-18)Repetitive transcranial magnetic stimulation (rTMS) modulates ongoing brain rhythms by activating neuronal structures and evolving different neuronal mechanisms. In the current work, the role of stimulation strength and ... -
Margin learning in spiking neural networks
(2018-11-29)The ability to learn, generalize and reliably detect features embedded in continuous sensory input streams is a crucial function of the central nervous system. Sensory neurons process input from thousands of synapses ...