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Validation of novel protein-protein interactions in Bacillus subtilis
(2023-01-12)Protein-protein interactions are the basis for many biological processes in the cell. Understanding these interactions is crucial for the general analysis of how the cell functions and the potential identification of ... -
Vav guanine nucleotide exchange factors control B cell antigen receptor-induced Ca2+-signaling
(2016-03-15)Differentiation of B cells into antibody secreting plasma cells is an indispensable step to cope with pathogens. Antigen binding to the B cell antigen receptor (BCR) initiates signaling cascades leading in combination with ... -
Vegetation dynamics of the East- European forest-steppe since the Late Glacial: climate, human and fire impact
(2024-03-11)While many studies have documented changes of the northern latitudinal forest limit in Europe and its drivers, little is known about the southern latitudinal limit of the forest towards the steppe in Eastern Europe. ... -
Vegetation patterns and processes in semi-natural open habitats and the contribution of wild red deer to their conservation
(2019-09-30)Traditional practices of human land use have shaped semi-natural open habitats over the past millennia, resulting in the typical European cultural landscapes with characteristic, diverse species communities. In the course ... -
Vegetation, climate and fire dynamics of Upper Montane Forest and Campos de Altitude during the Holocene in southeastern Brazil
(2020-09-22)The Atlantic Forest biome is well known as one of the mostly biodiversity regions on earth, hosting high species endemism and species/area ratio. It stretches around 1,300,000 km2 along the Brazilian coast between latitudes ... -
Vergleichende Untersuchungen zur Regulation der SNARE-Komplexbildung durch Sec1/Munc18-Proteine
(2009-07-01)Membrane fusion events between various intracellular compartments in eukaryotic cells are mediated by two conserved protein families: SNARE- and Sec1/Munc18 (SM)-proteins. The SNARE ... -
Vimentin Intermediate Filament Softening - Recovery Behavior and Post-Translational Modifications
(2021-09-16)The capability of eukaryotic cells to resist large deformations, to transport intracellular cargo and to adapt the cell shape, for example during migration, depends on the cytoskeleton, a composite network of three types ... -
Vision, cortical maps and neuronal plasticity in Bassoon and PSD-95 mutant mice.
(2014-03-21)Bassoon mutant mice (Bsn-/-) display a striking loss of synaptic ribbons in photoreceptor terminals, which impairs signal transduction through the retina (Altrock et al., 2003; Specht et al., 2007). Therefore we assessed ... -
Visual and Auditory Perceptual Decision-Making in The Human Brain as Invesitgated by fMRI and Lesion Studies
(2017-07-27)Perceptual decision-making refers to the act of choosing one option from a set of alternatives based on the available sensory information. In this manuscript, we used model-based functional magnetic resonance imaging and ... -
Visual information processing, welfare, and cognition in the rhesus macaque
(2017-10-20)Visual information processing, welfare, and cognition in the rhesus macaque - Chapter one deals with motion and disparity in macaque monkeys' area MST and their functional independence. Chapter two relates with the advantages ... -
Visualization of synaptic vesicle protein recycling during exo-endocytosis at individual hippocampal boutons
(2006-02-20)Upon exocytosis synaptic vesicle proteins are released into the plasma membrane and must be retrieved by compensatory endocytosis. When overexpressing GFP-labeled versions of the vesicle ... -
Vitamin B6 metabolism and underground metabolic routes in the Gram-positive bacterium Bacillus subtilis
(2021-07-16)Genome-reduced bacteria give the opportunity to study essential gene functions but also give the starting point for biotechnological production pathways. The MiniBacillus project aims to produce a genome reduced Bacillus ... -
Vitamin B6 Production in Bacillus subtilis
(2018-01-23)Fermentative production of valuable goods is an economically competitive and ecologically sustainable alternative to chemical synthesis. Several previous studies have been dedicated to the establishment of vitamin B6 ... -
Voltage-gating and assembly of split Kv10.1 channels
(2016-07-04)Voltage-gated ion channels allow ions to pass cell membrane upon changes of transmembrane electrical potential. Conformational changes in the voltage-sensing domain of the channel (VSD) are assumed to be transmitted to the ... -
Vulnerability analysis of the rare woodland fern Polystichum braunii (Dryopteridaceae) in Germany
(2017-10-18)Background: Various rare and endangered temperate ferns are being threatened by their recent population decline, but there is limited understanding of the causes behind it. Aims: This study attempted to identify the ... -
Weakly Selective Training induces Specialization within Populations of Sensory Neurons
(2016-12-16)Many neurons in sensory pathways respond selectively to a narrow class of stimuli such as faces or specific communication calls. At the same time neural processing is robust to a large degree of natural variablity ... -
White matter integrity of the frontal brain and its relevance for catatonia and executive function
(2021-11-22)Catatonia is a CNS derived psychomotor syndrome comprising disturbed volition and aberrant motor and behavioral features. Targeted and effective treatment today is scarce and further impeded by its heterogeneous clinical ... -
Wif1 Inhibits the Growth of Basal Cell Carcinoma
(2015-12-22)Basal cell carcinoma (BCC) belongs to the group of non-melanoma skin cancers and is the most commonly diagnosed cancer in fair-skinned individuals. In the majority of BCC the tumor suppressor gene patched1 (PTCH) is ... -
Wiring and information processing in the olfactory bulb of larval Xenopus laevis
(2020-02-04)Olfactory systems of vertebrates have adapted to the various challenges of their environments on both the level of odorant receptors and neuronal wiring. Amphibians like the African clawed frog Xenopus laevis offer a ... -
XDazl function in RNA metabolism in Xenopus laevis
(2015-11-25)Germ cell specification in Xenopus laevis depends on the inheritance of maternal determinants from the oocyte in form of mRNAs and proteins. At the onset of zygotic transcription, maternal mRNAs are subjected to miR-mediated ...