Browsing Human- und Zahnmedizin by Referee "Zerr, Inga Prof. Dr."
Now showing items 21-40 of 42
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Evaluation des Göttinger Kooperationsprojekts FIDEM (Frühe Informationen und Hilfen bei Demenz): Projekt-Etablierung und Erfahrungen von ärztlichen sowie nicht-ärztlichen Beteiligten
(2024-02-21)Early information and support in dementia (FIDEM) is a cooperation model that focuses on networking between general practitioners and non-medical cooperation partners (e.g. occupational therapists, care counselling, other ... -
Genetische Creutzfeldt-Jakob-Krankheit in Deutschland (1993-2010) - Charakterisierung dreier häufiger Mutationen in Abgrenzung zur sporadischen Creutzfeldt-Jakob-Krankheit und eine klinische Darstellung von seltenen Mutationen
(2014-04-01)This dissertation presents common and rare genetic CJD in their clinical presentation. The aim was to find a differentiation between the sporadic CJD and the common genetic CJD E200K and V210I. The other part was a clinical ... -
Gesamt-Tau, pTau, pTau rel, Beta-Amyloid 1-42 und 1-40 sowie Transthyretin in der Differentialdiagnostik neurodegenerativer Erkrankungen
(2022-11-01)New criteria have been published by the National Institute on Aging (NIA) and Alzheimer Association (AA) to define Alzheimer’s disease through the ATN classification system. The ATN classification system is based on ... -
Heart-Fatty Acid Binding Protein und α-Synuklein im Serum als mögliche Markerkandidaten für Parkinson und Demenz
(2018-02-28)Parkinson’s disease is a frequent neurodegenerative disease and dementia one of the complications that affects patients life quality significantly. So far the pathological mechanisms leading to Parkinson’s disease aren't ... -
Heterogenität von Prionprotein-Isoformen im Liquor cerebrospinalis von Patienten mit verschiedenen Typen von Prionenerkrankungen: Eine Charakterisierung unter Betrachtung zwölf monoklonaler PrP-Antikörper
(2022-01-11)The cellular prion protein is a multifunctional, evolutionarily highly conserved and ubiquitously expressed protein. It goes through a number of modifications during its post-translational processing, resulting in various ... -
Immunologisches Profil und PrPC-Expression von Patienten mit subkortikaler vaskulärer Enzephalopathie und vaskulärem kognitivem Impairment
(2017-03-02)The impact of vascular cognitive impairment (VCI) in society is increasing. Subcortical vascular encephalopathy (SVE) is the most common cause of VCI and is manifested mainly by White Matter Lesions (WMLs) and clinical ... -
Klinische und diagnostische Eigenschaften der sporadischen Creutzfeldt-Jakob-Krankheit bei Patienten mit positiver Familienanamnese für Demenz oder Morbus Parkinson
(2016-06-16)OBJECTIVE It was suggested that the cause of sporadic Creutzfeldt-Jakob disease (sCJD) is a spontaneous change in configuration of the prion protein. The acceptance of the influence of the misfolded protein chains which ... -
Lipocalin 2 als liquor und plasmabasierter Biomarker bei vaskulärer Enzephalopathie: Assoziationen mit klinischen Merkmalen und verschiedenen Formen der vaskulären Demenz
(2023-05-30)Diagnosing vascular dementia can be a significant challenge due to numerous differential diagnoses and overlapping clinical features. To supplement current neuropsychological and imaging diagnostic tools with an objective ... -
Liquormarker in der Diagnostik bei Patienten mit Morbus Parkinson, Parkinson-Demenz-Komplex und Morbus Alzheimer
(2015-09-24)Suffering from dementia, such as Alzheimer’s disease ("AD") and Parkinson’s disease with dementia ("PDD"), has far-reaching consequences for the patient’s self-determined life. In contrast to Alzheimer’s disease, there’s ... -
Liquorveränderungen bei Meningeosis neoplastica - eine retrospektive Studie (2001-2012) -
(2018-03-28)Background Meningeosis neoplastica is a diffuse metastatic spread of tumor cells in the subarachnoid space. Although first recognized in 1870, systematic investigations regarding cerebrospinal fluid (CSF) constituents in ... -
Magnetresonanztomographie bei Patienten mit der E200K- und V210I-Mutation
(2014-10-10)Prion diseases are a group of rare infectious neurodegenerative disorders, which are caused by aggregation of the misfolded pathological prion protein. Three subtypes can be distinguished according to their etiology: ... -
MMSE-Präprogressionsrate als potentieller Prädikator des kognitiven und funktionellen Progresses der Alzheimer-Demenz
(2017-05-22)For many years studies tried to predict the progress of Alzheimer’s disease (AD), but until finishing this work no examination techniques have reached the clinical stage. The preprogression rate (PPR) was first mentioned ... -
Prädiktive Diagnostik der Alzheimer Erkrankung
(2022-04-22)The National Institute of Aging and Alzheimer's Association’s diagnostic recommendations for preclinical Alzheimer’s disease (AD) and mild cognitive impairment (MCI) define AD by pathological processes which can be detected ... -
Quantitative analysis of neuropathological alterations in two transgenic mouse models of Alzheimer's disease
(2016-11-03)Mouse models of Alzheimer’s Disease (AD) contribute a lot to the understanding of etiology and pathology of AD. However, the entire clinical and neuropathological pictures of familial or sporadic AD in humans cannot be ... -
Risikofaktoren der sporadischen Creutzfeldt-Jakob-Krankheit
(2008-10-24)Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common form of human transmissible spongiform encephalopathies, but it s cause is still elusive. In this dissertation a case-control ... -
RT-QuIC-Assay zur Detektion von BSE in Rindern im Vergleich zu anderen Proteinaggregat-Detektionsverfahren
(2024-09-25)Bovine spongiform encephalopathy (BSE) is a transmissible neurodegenerative disease with fatal outcome. Occurring in cattle it can be transferred to humans via the food chain causing variant Creutztfeldt-Jakob disease ... -
Untersuchung von Proteomveränderungen im Synaptosom von Patienten mit sporadischer Creutzfeldt-Jakob-Krankheit
(2013-03-07)Sporadic Creutzfeldt-Jakob disease (sCJD) is characterized by wide clinical and pathological variability. This heterogeneity might be caused by the involvement of different molecular pathways depending on the prion agent ... -
Untersuchungen zu Amyloid-β-Peptiden im humanen Blutplasma als Biomarkerkandidaten der Alzheimerkrankheit
(2022-01-14)A selectively reduced concentration of Aβ1-42 and a low A β1-42/1-40 ratio in cerebrospinal fluid (CSF) are well-known biomarkers for Alzheimer´s Disease. Compared to the measurements in CSF, the examination of biomarkers ... -
Vergleich klinischer und paraklinischer Charakteristika zwischen rapid progressiven und „klassischen“ Verlaufsformen der Alzheimer- Erkrankung
(2023-10-25)Alzheimer's disease is the most common neurodegenerative dementia, and its prevalence is expected to triple worldwide in the coming decades. The individual course of the disease in Alzheimer's dementia is very heterogeneous. ... -
Wirkung der Ganzkörperkältetherapie auf psychologische und biologische Parameter – Implikationen für die Therapie bestimmter stressassoziierter psychischer Erkrankungen
(2023-04-27)Whole-body cryotherapy is a short-term physical therapy in which subjects stay in a -110 °C cold chamber for a maximum of three minutes. The purpose of this study was to investigate the effects of whole-body cryotherapy ...