Browsing Human- und Zahnmedizin by Advisor & Referee "Zerr, Inga Prof. Dr."
Now showing items 1-20 of 62
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Neurodegenerationsmarker im Verlauf eines 6-wöchigen hochfrequenten standardisierten Sportprogramms (SIWAS) in 3 Gruppen Psychiatrischer Erkrankungen
(2025-04-28)This study investigated the effects of a six-week, structured physical exercise program on neurodegenerative biomarkers in patients with schizophrenia, depression, or substance use disorders. A total of 61 participants ... -
Eine Untersuchung von Biomarker-Profilen bei Patienten im Spektrum zwischen Alzheimer-Demenz und vaskulärer Demenz
(2025-02-10)Developing dementia significantly alters the everyday life and quality of life of the affected patients. In the end stage of dementia, the diseased often experience complete helplessness and need for care. In contrast to ... -
Neuronal-exosomes biomarkers from plasma of neurodegenerative disease patients
(2025-01-21)The dementia group of diseases share some features such as the degeneration of neurons, which leads to progressive and irreversible loss of cognitive functions. Since almost 10 years, dementia syndromes were declared a ... -
Untersuchung plasmabasierter Kompositbiomarker in der Differentialdiagnostik von Alzheimer-Demenz und Vaskulärer Demenz
(2025-01-17)Due to demographic change, dementia is not only at the center of medical research but is also becoming increasingly important in the health economic and social debate. Taking that into consideration, dementia diagnostics ... -
Investigation on female and male hippocampal neurons
(2024-11-12)There is no doubt that there are differences between the sexes. According to present knowledge, they start with the question of whether an individual inherits a second X chromosome or a Y chromosome. From this point ... -
RT-QuIC-Assay zur Detektion von BSE in Rindern im Vergleich zu anderen Proteinaggregat-Detektionsverfahren
(2024-09-25)Bovine spongiform encephalopathy (BSE) is a transmissible neurodegenerative disease with fatal outcome. Occurring in cattle it can be transferred to humans via the food chain causing variant Creutztfeldt-Jakob disease ... -
Evaluation des Göttinger Kooperationsprojekts FIDEM (Frühe Informationen und Hilfen bei Demenz): Projekt-Etablierung und Erfahrungen von ärztlichen sowie nicht-ärztlichen Beteiligten
(2024-02-21)Early information and support in dementia (FIDEM) is a cooperation model that focuses on networking between general practitioners and non-medical cooperation partners (e.g. occupational therapists, care counselling, other ... -
Vergleich klinischer und paraklinischer Charakteristika zwischen rapid progressiven und „klassischen“ Verlaufsformen der Alzheimer- Erkrankung
(2023-10-25)Alzheimer's disease is the most common neurodegenerative dementia, and its prevalence is expected to triple worldwide in the coming decades. The individual course of the disease in Alzheimer's dementia is very heterogeneous. ... -
Lipocalin 2 als liquor und plasmabasierter Biomarker bei vaskulärer Enzephalopathie: Assoziationen mit klinischen Merkmalen und verschiedenen Formen der vaskulären Demenz
(2023-05-30)Diagnosing vascular dementia can be a significant challenge due to numerous differential diagnoses and overlapping clinical features. To supplement current neuropsychological and imaging diagnostic tools with an objective ... -
Wirkung der Ganzkörperkältetherapie auf psychologische und biologische Parameter – Implikationen für die Therapie bestimmter stressassoziierter psychischer Erkrankungen
(2023-04-27)Whole-body cryotherapy is a short-term physical therapy in which subjects stay in a -110 °C cold chamber for a maximum of three minutes. The purpose of this study was to investigate the effects of whole-body cryotherapy ... -
Retrospektive epidemiologische Untersuchung des Zusammenhangs zwischen der Erkrankung mit sCJK und dem ärztlichen Beruf in Deutschland. Eine Studie mit Patientendaten von 1993 bis 2016.
(2022-11-04)The aim of the present study was to identify a possible risk factor for sporadic Creutzfeldt-Jakob disease (sCJD) through professional activity as a physician. For this purpose a retrospective cohort analysis was performed ... -
Gesamt-Tau, pTau, pTau rel, Beta-Amyloid 1-42 und 1-40 sowie Transthyretin in der Differentialdiagnostik neurodegenerativer Erkrankungen
(2022-11-01)New criteria have been published by the National Institute on Aging (NIA) and Alzheimer Association (AA) to define Alzheimer’s disease through the ATN classification system. The ATN classification system is based on ... -
Idiopathisches Parkinson Syndrom und a-Synuclein im Liquor: Bio- und Prognosemarker für Kognition, Krankheitsverlauf und depressive Symptomatik?
(2022-10-18)Bradykinesia, tremor and rigor are the main clinical features by which Parkinson’s Disease (PD) has been diagnosed clinically since the first describer, James Parkinson. A diagnosis-supporting biomarker does not exist yet. ... -
Einfluss von prä-analytischen Entnahme- und Lagerungsbedingungen auf die Stabilität und Konzentration von Amyloid-ß-Peptiden in Blut
(2022-06-29)In an increasingly aging population, age-related diseases such as dementia play a central role. Expecting an increase of the number of patients suffering from dementia worldwide, dementia-related research is becoming more ... -
Prädiktive Diagnostik der Alzheimer Erkrankung
(2022-04-22)The National Institute of Aging and Alzheimer's Association’s diagnostic recommendations for preclinical Alzheimer’s disease (AD) and mild cognitive impairment (MCI) define AD by pathological processes which can be detected ... -
Die Bedeutung sensibler und autonomer Ganglien in der Pathogenese der sporadischen Creutzfeldt-Jakob-Erkrankung unter Berücksichtigung des PrPsc-Typs
(2022-02-17)Abstract Background: In sporadic Creutzfeldt-Jakob disease (sCJD), the pathological changes appear to be restricted to the central nervous system. Only involvement of the trigeminal ganglion is widely accepted. Objective: ... -
Untersuchungen zu Amyloid-β-Peptiden im humanen Blutplasma als Biomarkerkandidaten der Alzheimerkrankheit
(2022-01-14)A selectively reduced concentration of Aβ1-42 and a low A β1-42/1-40 ratio in cerebrospinal fluid (CSF) are well-known biomarkers for Alzheimer´s Disease. Compared to the measurements in CSF, the examination of biomarkers ... -
Heterogenität von Prionprotein-Isoformen im Liquor cerebrospinalis von Patienten mit verschiedenen Typen von Prionenerkrankungen: Eine Charakterisierung unter Betrachtung zwölf monoklonaler PrP-Antikörper
(2022-01-11)The cellular prion protein is a multifunctional, evolutionarily highly conserved and ubiquitously expressed protein. It goes through a number of modifications during its post-translational processing, resulting in various ... -
Analyse der Diagnosekriterien der Creutzfeldt-Jakob-Erkrankung in Deutschland
(2021-11-29)The Creutzfeldt-Jakob disease (CJD) is the most common prion disease. With an incident of 1.5 cases per 1,000,0000 inhabitants in Germany around 120 people (97% of all prion disease cases) are diagnosed with this disease ... -
Ethische Implikationen der Prädiktion und Früherkennung einer Late-onset-Demenz
(2021-06-24)The focus on diagnosing dementia as early as possible has entered clinical practice, often supported by the use of an increasing number of available biomarkers. New diagnostics in this topic area are the subject of intense ...