Dokumente Human- und Zahnmedizin nach Gutachter "Virsik-Köpp, Patricia Prof. Dr."
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Differenzielle Regulation und prognostische Bedeutung von zellzyklusassoziierten Regulatoren der G1- und G2-Phase in Abhängigkeit von der anatomischen Lokalisation in Gastrointestinalen Stromatumoren (GIST)
(2010-09-09)AIM: Gastrointestinal stromal tumors (GIST) belong to the most common mesenchymal GI neoplasms (70%). Generally, gastric GISTs show a more favourable clinical outcome compared to GISTs from ... -
Effekte von Estradiol und Raloxifen sowie der pflanzlichen Substanzen Agnus castus, Belamcanda chinensis und Silybum marianum im Brustgewebe der ovarektomierten Ratte im Hinblick auf das Mammakarzinomrisiko
(2013-02-27)Menopausal symptoms can affect the general health of women strongly negative. Not only women in the natural or surgical menopause, but also women with an antihormontherapy with tamoxifen or aromatase-inhibitors + /. GNRH ... -
Effizienz niedrig- und hochkonzentrierter Fluoridpräparate zur Erosionsprophylaxe am humanen Schmelz
(2013-08-15)The purpose of the study was the assessment of the efficacy of low- or high-concentrated fluoride agents for the protection of the enamel surface against erosion, using the non-invasive method of quantitative light-induced ... -
Einfluss der atrialen Überstimulation mit zwei Frequenzen auf nächtliche Atemstörungen
(2012-06-20)Atrial overdrive pacing markedly improved sleep disordered breathing in a recent study. Using a single blinded, randomized, crossover design, we aimed to reproduce these findings and investigate the possible underlying ... -
Einfluss der intermittierenden PTH-Applikation (hPTH 1-34) auf die Frakturheilung des metaphysären Knochens der orchiektomierten Ratte
(2012-03-12)Influence of human parathyroid hormone (hPTH 1-34) on bone healing was studied in either orchiectomized (Orx at 8 months of age) or sham-operated male rats.Eleven-month-old Sprague Dawley ... -
Einfluss der transkraniellen Gleichstromstimulation auf die stimmungsabhängige Informationsverarbeitung bei gesunden Probanden
(2012-01-03)The left dorsolateral prefrontal cortex is involved in emotional processing and mood generation. Cellular hypoactivity in this area results in depressive symptoms. Using non-invasive tools ... -
Der Einfluss von 20-Hydroxyecdysone und 17-β-Östradiol auf den Knochenmetabolismus der ovarektomierten Sprague-Dawley-Ratte: Eine Alternative der postmenopausalen Antiosteoporosetherapie?
(2011-11-07)20-Hydroxyecdysone (ECD) is a Phytoecdysteroid with anabolic and osteoprotective effects. The aim of this study was to investigate whether Ecd can be used as a potential treatment alternative ... -
Endovaskulär interventionelles Notfallmanagement des akuten A. carotis-interna-Verschlusses
(2013-11-04)Untreated acute occlusion of the internal carotid artery (ICA) comes along with high morbidity and mortality. The incidence rate is about 6 per 100000 persons a year. While for treatment of ICA stenosis interventional stent ... -
Epidemiologie und Empfindlichkeit von Pilzisolaten gegenüber sechs Antimykotika aus primär sterilen Materialien in Deutschland
(2012-08-02)The incidence of invasive candidiasis continuously increased worldwide over the last two decades. Epidemiological data for Germany are rare to date. Five hundred and sixty-seven isolates from the strain collection of the ... -
Ereignisbezogene Hirnpotentiale bei statischen und bewegten visuellen Reizen. Ein Vergleich von Jungen mit Aufmerksamkeitsdefizit- Hyperaktivitätsstörung und deren gesunden Altersgenossen.
(2012-06-12)The research concerning attention deficit hyperactivity disorder (ADHD), involving inattention, impulsivity and hyperactivity, increased in the last years. While solving tasks which require cognitive control processes, the ... -
Erkennung diagnostischer Frühmarker der Nierenfibrose beim Tiermodell des Alport-Syndroms mittels proteomischer Methoden
(2013-03-05)Alport syndrome is a progressive, hereditary nephropathy which is characterized by typical changes in the basement membrane leading to proteinuria and hematuria. Proteines, which then pass the glomerular filter, occurring ... -
Erste Erfahrungen mit der Micro-Diagonalpumpe Deltastream® der Firma Medos (Helmholtz Institut Aachen) als linksventrikulärem Herzunterstützungssystem (LVAD) mit pulsatiler und laminarer Perfusion am Schafsmodell über sieben Tage.
(2011-12-15)In the western industrialized countries heart failure is currently one of the most common internal diseases. In the final stage of this disease heart transplantation is the treatment of ... -
Experimental study of the combined effect of irradiation, lovastatin, and monoclonal antibodies on tumour and normal tissue cell lines. Its genesis and mechanisms of action
(2014-09-30)Statins, as lipid-lowering agents, were described to possess an anti-cancer potential. For this reason, in vitro effect of combined treatment by lovastatin and irradiation was explored in order to find a radiosensitizing ... -
Experimentelle Untersuchung zur Wirkung von in Tumorzellen produziertem Keratinozytenwachstumsfaktor (KGF) auf die proliferative Aktivität und Strahlenreaktion von Tumoren und Normalgewebe
(2011-03-07)Purpose of this work was to test the effect of tumour-cell-derived keratinocyte growth factor (KGF) or recombinant KGF (palifermin) on cell proliferation and radiation response of human ... -
Expression der kostimulatorischen Moleküle ILA (CD137) und ICOS (CD278) sowie ihrer Liganden auf Mastzellen und T-Zellen der Haut von Patienten mit Psoriasis vulgaris
(2011-11-02)In this study the expression of the co-stimulatory molecules ILA receptor (ILA, "induced by lymphocyte activation", CD137 in humans and 4-1BB in mice) from the TNF receptor family and ICOS ... -
Die Expression von Sulfattransportern als Funktion einer fortschreitenden Nierenfibrose am Modell der Alport-Maus
(2012-01-13)The system of sulfate metabolism and the expression of sulfate transporters in kidney and liver tissue are influenced by various parameters. The focus of this thesis lies on the sulfate ... -
Fournier-Gangrän: Krankheitsverlauf in Abhängigkeit von Komorbiditäten und Therapie
(2012-08-02)Fournier's gangrene is defined as a necrotizing fasciitis of the perineal, genital or perianal region which is often caused by a synergistical infection of aerobic and anaerobic agents. Its potentially lethal course ... -
Funktionelle Analyse des keimzellspezifischen Gens ADAM 27
(2011-06-29)The members of ADAM gene family can have both, cell adhesion and/or protease activity, due to their typical domain structure. ADAM 27 is exclusively expressed in testis and seems to be ... -
Funktionelle Analyse des Prostate-derived-Ets-Factors (PDEF) in der Prostatakarzinomzelllinie LNCaP
(2011-05-09)PDEF a co-regulator of the androgen receptor shows a marked tumour-associated expression. The role of PDEF in cancer cell invasiveness is currently under investigation. To study the function ... -
Funktionelle Charakterisierung der mit altersabhängiger Makuladegeneration (AMD) assoziierten Komplementfaktor-H-Variante Y402H
(2012-02-10)Factor H (FH) is the most important regulator of alternative pathway Complement activation in the fluid phase. The FH-polymorphism Y402H which is strongly associated with age-related macular ...