Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Wimmer, Ernst A. Prof. Dr."
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Funktionelle Analysen deregulierter Signalwege transformierter B-Lymphozyten - Das Epstein-Barr-Virus-Onkogen LMP1
(2007-06-20)The development of different tumor entities can often be correlated with a viral infection. One of this tumor associated viruses is the Epstein-Barr virus (EBV). More than 90% of the human ... -
Funktionelle Charakterisierung potentieller Pathogenitätsfaktoren aus Pseudomonas aeruginosa mittels biochemischer und evolutiver Methoden
(2005-07-15)Three novel potential pathogenicity factors from the opportunistic pathogen Pseudomonas aeruginosa were characterized functionally and biochemically. The P. aeruginosa mutant 41D3 carries ... -
Genetic Evidence For Neuron-Glia Metabolic Coupling In The CNS
(2016-07-27)The active contribution of oligodendrocytes and astrocytes to sustain brain physiology was completely underestimated, but severe consequences of their dysfunction in various diseases and glia-specific mutants emphasized ... -
Gesangskontrolle durch Neurone des Zentralkomplexes: Physiologische und immunzytochemische Untersuchungen an primären Zellkulturen aus dem Feldheuschreckengehirn
(2008-08-20)Acridid grasshoppers communicate with specific song patterns in the context of attracting partners for reproduction, courting and agonistic behavior. When to sing and which song pattern ... -
Human and mouse meniscus progenitor cells and their role in meniscus tissue regeneration
(2014-05-19)Osteoarthritis (OA) is a degenerative disease of hyaline cartilage. The cartilage is an avascular tissue, once damaged it is difficult to repair. Articular cartilage is responsible for the smooth, frictionless, and painless ... -
Identification and Characterization of Novel Genes involved in Quinone Synthesis in the Odoriferous Defensive Stink Glands of the Red Flour Beetle, Tribolium castaneum
(2021-05-26)Defense strategies are common in insects including Coleoptera, the largest animal taxon containing various types of beetles. Stink gland secretion of beetles is playing an important role in their defense against detrimental ... -
Identification and Functional Characterization of Trans-acting Factors Involved in Vegetal mRNA Localization in Xenopus Oocytes
(2008-07-24)Directional transport of specific mRNAs is a mechanism for the generation of asymmetry which is of primary biological importance. In Xenopus oocytes, mRNA localization to the vegetal ... -
Identifikation von Zielen und molekulare Charakterisierung des RNA-Bindeproteins XSeb4R in Xenopus laevis
(2009-10-28)While developmental processes have been extensively studied in the context of transcriptional regulation, much less is known about regulation via translational regulation. RNA-binding ... -
Identifizierung neuer Coregulatoren von SOX9 und RUNX2 in chondrogenen Progenitorzellen in der Osteoarthrose
(2015-06-23)Osteoarthritis is a degenerative disease of the joints. It is characterized by a successive destruction of the articular cartilage and surrounding structures. Osteoarthritis is the most common musculoskeletal joint disease ... -
Identifizierung neuer vegetal lokalisierter RNAs in der Xenopus laevis Oozyte und deren funktionelle Charakterisierung
(2005-12-16)Vegetally localized mRNA molecules in Xenopus laevis oocytes play important roles in the formation of the primary germ layers and the germ line. In order to identify novel vegetally localized ... -
Identifizierung schutzvermittelnder Antigene von Aspergillus fumigatus für eine Impfstoffentwicklung zur Verhütung invasiver Aspergillosen bei Leukämie-Patienten
(2015-01-23)A.fumigatus is the most common cause of invasive, usually fatal aspergillosis in severely immunocompromised patients. A natural resistance to the fungus is mediated by the innate immune system. Additionally, an acquired ... -
Identifizierung und funktionelle Charakterisierung neuer RNA-Transportfaktoren in der Xenopus laevis Oozyte
(2008-06-05)RNA localization is an important strategy to create intracellular asymmetry and plays an essential role in early embryogenesis in several organisms. Revealing the molecular mechanism of ... -
Large Dense Core Vesicle Exocytosis in Mouse Chromaffin Cells is Regulated by Munc13s and Baiap3
(2008-12-16)Members of mammalian uncoordinated 13 protein family (Munc13s) are essential for SV exocytosis in neurons and have also been implicated in LDCV exocytosis in chromaffin cells. However, ... -
Mammalian spermiogenesis and the formation of the sperm head to tail coupling apparatus
(2021-08-24)The head-tail coupling apparatus (HTCA), also known as connecting piece, provides the physical linkage between the sperm head and its tail. The HTCA morphogenesis initiates during spermiogenesis and is assembled at the ... -
Metabolic synchronization of the liver circadian clock
(2012-09-28)The daily rotation of the earth around its axis determines the day length of 24 hours and the periodic change from day to night. Organisms evolved endogenous clocks to anticipate the light/dark alteration and associated ... -
Modelling genetic heart diseases with patient-specific induced pluripotent stem cells
(2014-09-23)Brugada syndrome (BrS), a cardiac genetic disease, is one of the major causes of sudden cardiac death in healthy young people. However, the underlying electrophysiological and molecular mechanisms have not been completely ... -
Molecular and Functional Characterization of Programmed Cell Death (PCD) in Toxoplasma gondii
(2013-05-06)Toxoplasma gondii is a protozoan parasite which leads to widespread infections in humans and animals worldwide. Infection is typically asymptomatic in immunocompetent hosts, but may lead to severe symptoms in immunocompromized ... -
Molecular evolution of primates - featuring mobile elements
(2009-03-12)With at least 66 genera and about 350 species, the order Primates is one of the most diverse mammalian orders. Even though the phylogenetic relationships among major lineages are elucidated, ... -
Molecular mechanisms governing germ line development in zebrafish and the role of this lineage in sexual differentiation
(2006-03-17)Primordial germ cells (PGCs) in zebrafish are specified early in the development by inheritance of a specific type of cytoplasm termed germ plasm. The asymmetrically distributed germ plasm ... -
Molecular mechanisms of myelin membrane biogenesis
(2008-03-26)During vertebrate brain development, axons are ensheathed by myelin, an insulating membrane generated by oligodendrocytes. Our aim is to elucidate the cellular machinery that is required for the formation of this membrane. ...