Browse by type "doctoralThesis"
Now showing items 1-20 of 5301
-
Coulomb Correlations in Femtosecond Electron Pulses
(2025-12-10)Electron beams are a key resource for exploring and manipulating objects on the nanometre scale. While the spatial, spectral, and temporal resolution of a dilute electron microscope beam is limited by imperfections in ... -
Establishing proximity-dependent protein labeling to investigate co-chaperone mediated effector secretion in Ustilago maydis
(2025-12-10)The complex process of protein folding within the endoplasmic reticulum (ER) of the corn smut fungi Ustilago maydis depends on the coordinated action of chaperone and their associated co-chaperone proteins. The unfolded ... -
Synthesis and characterization of fluorescent probes targeting Histone Deacetylase 6 for live cell imaging
(2025-12-10)Histone Deacetylase 6 (HDAC6) is a unique enzyme that plays a central role in major cellular processes, including cytoskeletal regulation, protein quality control, and stress responses. Its dysregulation is linked to many ... -
β-Hydrogen Eliminations from Organoaluminates and -Cuprates in the Gas Phase
(2025-12-10)The β-hydride elimination is a fundamental process in many organometallic reaction mechanisms and decomposition pathways. This thesis investigates the β-hydride elimination of alkyl organoaluminates and alkyl organocuprates ... -
Learning the shape of neurons: Representation learning, generative modeling and hierarchical clustering
(2025-12-10)The remarkable diversity of neuronal morphologies has continued to fascinate researchers since Ramón y Cajal's pioneering work in 1911. A neuron's dendritic shape determines the inputs it receives, and, consequently, the ... -
Designing a System for Tracking and Spatio-Temporal Action Classification of Primates
(2025-12-10)Primate researchers in both laboratory settings and natural environments are fundamentally interested in primate behavior. Approaches range from controlled laboratory setups enabling implant-based neuronal recordings to ... -
Investigating biocompatibility of super-resolution compatible fluorescent DNA probes in mouse living tissues
(2025-12-08)Fluorescence nanoscopy allows the observation of living biological structures at the nanometer scale. However, choosing the best fluorophore for in-vivo imaging often is a challenging task as systematic studies investigating ... -
Resolving intermediate states of mitotic entry
(2025-12-08)Mitosis, the division of cells, is a fundamental biological process essential for growth, tissue repair, and the propagation of genetic material. Mitosis is tightly regulated and its dysregulation has severe consequences, ... -
Achieving Scalable AI Inference in a Unified Cloud and HPC Environment by Employing System of Systems Architecture Design
(2025-12-04)Providing access to AI powered services commonly requires access to powerful compute infrastructure equipped with hardware accelerators such as GPUs. The recent rise of LLMs further emphasized this need and already caused ... -
Generation and characterization of an otic bioengineered neuronal organoid (oBENO) from human pluripotent stem cells
(2025-12-03)Hearing loss impacts nearly 20% of the global population, and according to estimations its prevalence will increase by 2050, affecting around 1 in 4 individuals. The most common form of hearing impairment, sensorineural ... -
Graph Neural Networks for Spatial Data Analysis: Theoretical Results and Applications
(2025-12-02)Overall, this thesis explores the advantages and challenges of spatial data prediction tasks with Graph Neural Networks (GNN). Kriging, the best linear unbiased predictor presents a great number of advantages over other ... -
OH NO! - Investigating the microsolvation of aminoxyl radicals via FTIR spectroscopy
(2025-12-02)This work investigates complexes of stable organic radicals with halogenated alcohols using FTIR jet spectroscopy combined with quantum chemical calculations. Due to the formation of a hydrogen bond, the OH stretching ... -
Development of ¹⁹F and ³¹P Dynamic Nuclear Polarization in the Liquid State
(2025-12-02)Within the last decades, nuclear magnetic resonance (NMR) spectroscopy in the liquid state has become one of the most powerful techniques allowing for the analysis of structures and dynamics of chemical systems at atomic ... -
Community assembly processes of intertidal salt marsh microarthropods
(2025-12-01)Salt marshes are highly dynamic ecosystems at the land–sea interface, shaped by steep environmental gradients and frequent disturbances. They provide critical ecosystem services, including coastal protection, nutrient ... -
Molecular and Physiological Mechanisms of Cabbage Stem Flea Beetle (Psylliodes chrysocephala) Aestivation
(2025-12-01)Seasonal dormancy is a key adaptation that enables insects to survive predictable periods of environmental stress. Aestivation, a form of summer diapause, prepares insects for high-temperature and low-humidity conditions ... -
Deriving Forest Structural and Functional Metrics from Airborne and Ground-based Mobile Laser Scanning
(2025-11-26)This study examined the application of LiDAR-based methods, specifically Airborne Laser Scanning (ALS) and ground-based Mobile Laser Scanning (MLS), to evaluate forest structural metrics and their ecological functions ... -
Stabilized Optical Scanning Tunneling Microscopy: Probing Defect-Driven Phenomena in Correlated Electron Systems
(2025-11-26)This thesis presents the development and application of a stabilized optical scanning tunneling microscopy (STM) approach that enables controlled, localized optical excitation at the atomic scale. A key advancement is the ... -
Polylactic acid as a binder for lignocellulosic-based insulation materials
(2025-11-26)This research explores the possible application of a renewable binder in the development of flexible insulation materials derived from lignocellulosic sources. These materials, based on lignocellulosic fibers, can be ... -
Bis(amidophenolate)-supported Pnictogen Complexes: Redox Activity, Cooperativity and Electromerism
(2025-11-26)This thesis describes the synthesis, characterization and reactivity of pnictogen compounds derived from the tetradentate, redox-active bis(amidophenolate) ligand, N,N′-bis(3,5-di-tert-butyl-2-phenoxy)-1,2-phenylenediamide. ... -
Measurement of the $t\bar{t}H$ Production Cross-Section in the Non-Resonant Four Lepton Final State in $pp$ Collisions at $\sqrt{s}=13\,\text{TeV}$ with the ATLAS Detector
(2025-11-26)This thesis presents the measurements of the associated production of a top quark pair with a Standard Model Higgs boson in multi-lepton final states, focusing on the measurement of the inclusive cross-section in the $4\ell$ ...